Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.cyto.2018.06.031
Title: Exercise alarms the immune system: A HMGB1 perspective
Authors: Goh, Jorming 
Behringer, Michael
Keywords: Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
Cell Biology
Immunology
Alarmins
Exercise
HMGB1
Immune
CELL-FREE DNA
SKELETAL-MUSCLE
MOBILITY
INFLAMMATION
DAMAGE
ORGAN
Issue Date: 1-Oct-2018
Publisher: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
Citation: Goh, Jorming, Behringer, Michael (2018-10-01). Exercise alarms the immune system: A HMGB1 perspective. CYTOKINE 110 : 222-225. ScholarBank@NUS Repository. https://doi.org/10.1016/j.cyto.2018.06.031
Abstract: The “danger” model of immunology states that the immune system detects and responds to danger by releasing endogenous molecules called alarmins. Strenuous exercise perturbs physiological homeostasis, increasing circulating alarmins to drive the inflammatory response. We describe a working concept of exercise-induced High Mobility Group Box (HMGB)1, a prototypical alarmin, in modulating immune responses and adaptations.
Source Title: CYTOKINE
URI: https://scholarbank.nus.edu.sg/handle/10635/219446
ISSN: 1043-4666
1096-0023
DOI: 10.1016/j.cyto.2018.06.031
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