Please use this identifier to cite or link to this item: https://doi.org/10.1126/scitranslmed.abj4124
Title: Point-of-care diagnostic tests for tuberculosis disease
Authors: Hong, Jia Mei 
Lee, Hyeyoung
Menon, Nishanth V 
Lim, Chwee Teck 
Lee, Luke P 
Ong, Catherine WM 
Issue Date: 6-Apr-2022
Publisher: American Association for the Advancement of Science (AAAS)
Citation: Hong, Jia Mei, Lee, Hyeyoung, Menon, Nishanth V, Lim, Chwee Teck, Lee, Luke P, Ong, Catherine WM (2022-04-06). Point-of-care diagnostic tests for tuberculosis disease. Science Translational Medicine 14 (639). ScholarBank@NUS Repository. https://doi.org/10.1126/scitranslmed.abj4124
Abstract: Rapid diagnosis is one key pillar to end tuberculosis (TB). Point-of-care tests (POCTs) facilitate early detection, immediate treatment, and reduced transmission of TB disease. This Review evaluates current diagnostic assays endorsed by the World Health Organization and identifies the gaps between existing conventional tests and the ideal POCT. We discuss the commercial development of new rapid tests and research studies on nonsputum-based diagnostic biomarkers from both pathogen and host. Last, we highlight advances in integrated microfluidics technology that may aid the development of new POCTs.
Source Title: Science Translational Medicine
URI: https://scholarbank.nus.edu.sg/handle/10635/218957
ISSN: 1946-6234
1946-6242
DOI: 10.1126/scitranslmed.abj4124
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