Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.copbio.2017.03.021
Title: Applying the design-build-test paradigm in microbiome engineering
Authors: Pham, Hoang Long 
Ho, Chun Loong 
Wong, Adison
Lee, Yung Seng 
Chang, Matthew Wook 
Keywords: Science & Technology
Life Sciences & Biomedicine
Biochemical Research Methods
Biotechnology & Applied Microbiology
Biochemistry & Molecular Biology
GUT MICROBIOTA
INTESTINAL MICROBIOTA
EARLY-LIFE
HOST
ANTIBIOTICS
BACTERIA
GENE
PERSISTENCE
TOOLS
Issue Date: 1-Dec-2017
Publisher: CURRENT BIOLOGY LTD
Citation: Pham, Hoang Long, Ho, Chun Loong, Wong, Adison, Lee, Yung Seng, Chang, Matthew Wook (2017-12-01). Applying the design-build-test paradigm in microbiome engineering. CURRENT OPINION IN BIOTECHNOLOGY 48 : 85-93. ScholarBank@NUS Repository. https://doi.org/10.1016/j.copbio.2017.03.021
Abstract: The recently discovered roles of human microbiome in health and diseases have inspired research efforts across many disciplines to engineer microbiome for health benefits. In this review, we highlight recent progress in human microbiome research and how modifications to the microbiome could result in implications to human health. Furthermore, we discuss the application of a ‘design-build-test’ framework to expedite microbiome engineering efforts by reviewing current literature on three key aspects: design principles to engineer the human microbiome, methods to engineer microbiome with desired functions, and analytical techniques to examine complex microbiome samples.
Source Title: CURRENT OPINION IN BIOTECHNOLOGY
URI: https://scholarbank.nus.edu.sg/handle/10635/216076
ISSN: 09581669
18790429
DOI: 10.1016/j.copbio.2017.03.021
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