Please use this identifier to cite or link to this item: https://doi.org/10.3390/cells8121634
Title: The Butterfly Effect of RNA Alterations on Transcriptomic Equilibrium
Authors: Desi, N. 
Tay, Y. 
Keywords: cancer
competing endogenous RNA
microRNA
post-transcriptional regulation
RNA alteration
RNA-binding protein
transcriptomic equilibrium
Issue Date: 2019
Publisher: NLM (Medline)
Citation: Desi, N., Tay, Y. (2019). The Butterfly Effect of RNA Alterations on Transcriptomic Equilibrium. Cells 8 (12). ScholarBank@NUS Repository. https://doi.org/10.3390/cells8121634
Rights: Attribution 4.0 International
Abstract: Post-transcriptional regulation plays a key role in modulating gene expression, and the perturbation of transcriptomic equilibrium has been shown to drive the development of multiple diseases including cancer. Recent studies have revealed the existence of multiple post-transcriptional processes that coordinatively regulate the expression and function of each RNA transcript. In this review, we summarize the latest research describing various mechanisms by which small alterations in RNA processing or function can potentially reshape the transcriptomic landscape, and the impact that this may have on cancer development.
Source Title: Cells
URI: https://scholarbank.nus.edu.sg/handle/10635/212176
ISSN: 2073-4409
DOI: 10.3390/cells8121634
Rights: Attribution 4.0 International
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