Please use this identifier to cite or link to this item: https://doi.org/10.1007/s00520-020-05803-4
Title: MASCC/ISOO clinical practice guidelines for the management of mucositis: sub-analysis of current interventions for the management of oral mucositis in pediatric cancer patients
Authors: Miranda-Silva, Wanessa
Gomes-Silva, Wagner
Zadik, Yehuda
Yarom, Noam
Al-Azri, Abdul Rahman
HSU LING CATHERINE HONG 
Ariyawardana, Anura
Saunders, Deborah P
Correa, M Elvira
Arany, Praveen R
Bowen, Joanne
Cheng Kin Fong Karis 
Tissing, Wim JE
Bossi, Paolo
Elad, Sharon
Keywords: Science & Technology
Life Sciences & Biomedicine
Oncology
Health Care Sciences & Services
Rehabilitation
Cancer
Prevention
Treatment
Oral mucositis
Pain
Pediatric patients
Evidence-based
Guidelines
STEM-CELL TRANSPLANTATION
COLONY-STIMULATING FACTOR
ACUTE LYMPHOBLASTIC-LEUKEMIA
LEVEL LASER THERAPY
DOUBLE-BLIND
CONTROLLED ANALGESIA
GLUTAMINE SUPPLEMENTATION
VIRIDANS STREPTOCOCCI
YOUNG-PATIENTS
CHEWING GUM
Issue Date: 6-Nov-2020
Publisher: SPRINGER
Citation: Miranda-Silva, Wanessa, Gomes-Silva, Wagner, Zadik, Yehuda, Yarom, Noam, Al-Azri, Abdul Rahman, HSU LING CATHERINE HONG, Ariyawardana, Anura, Saunders, Deborah P, Correa, M Elvira, Arany, Praveen R, Bowen, Joanne, Cheng Kin Fong Karis, Tissing, Wim JE, Bossi, Paolo, Elad, Sharon (2020-11-06). MASCC/ISOO clinical practice guidelines for the management of mucositis: sub-analysis of current interventions for the management of oral mucositis in pediatric cancer patients. SUPPORTIVE CARE IN CANCER 29 (7) : 3539-3562. ScholarBank@NUS Repository. https://doi.org/10.1007/s00520-020-05803-4
Abstract: Objective: The aim of this sub-analysis was to highlight the MASCC/ISOO clinical practice guidelines for the management of oral mucositis (OM) in pediatric patients and to present unique considerations in this patient population. Methods: This sub-analysis of the pediatric patient population is based on the systematic review conducted by the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISSO) published in 2019/2020. Studies were scored and assigned a level of evidence based on previously published criteria. Data regarding adverse effects and compliance was collected from the original publications. Results: A total of 45 papers were included and assessed in this sub-analysis, including 21 randomized controlled trials (RCTs). Chewing gum was demonstrated to be not effective in preventing OM in pediatric cancer patients in 2 RCTs. The efficacy of all other interventions could not be determined based on the available literature. Conclusion: There is limited or conflicting evidence about interventions for the management of OM in pediatric cancer patients, except for chewing gum which was ineffective for prevention. Therefore, currently, data from adult studies may need to be extrapolated for the management of pediatric patients. Honey and photobiomodulation therapy in this patient population had encouraging potential. Implementation of a basic oral care protocol is advised amid lack of high level of evidence studies.
Source Title: SUPPORTIVE CARE IN CANCER
URI: https://scholarbank.nus.edu.sg/handle/10635/207316
ISSN: 0941-4355
1433-7339
DOI: 10.1007/s00520-020-05803-4
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
Support Care Cancer Ped Sub Analysis 2020.pdf17.41 MBAdobe PDF

CLOSED

Published

SCOPUSTM   
Citations

14
checked on Sep 23, 2022

Page view(s)

81
checked on Sep 22, 2022

Download(s)

2
checked on Sep 22, 2022

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.