Please use this identifier to cite or link to this item: https://doi.org/10.1007/s00520-020-05803-4
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dc.titleMASCC/ISOO clinical practice guidelines for the management of mucositis: sub-analysis of current interventions for the management of oral mucositis in pediatric cancer patients
dc.contributor.authorMiranda-Silva, Wanessa
dc.contributor.authorGomes-Silva, Wagner
dc.contributor.authorZadik, Yehuda
dc.contributor.authorYarom, Noam
dc.contributor.authorAl-Azri, Abdul Rahman
dc.contributor.authorHSU LING CATHERINE HONG
dc.contributor.authorAriyawardana, Anura
dc.contributor.authorSaunders, Deborah P
dc.contributor.authorCorrea, M Elvira
dc.contributor.authorArany, Praveen R
dc.contributor.authorBowen, Joanne
dc.contributor.authorCheng Kin Fong Karis
dc.contributor.authorTissing, Wim JE
dc.contributor.authorBossi, Paolo
dc.contributor.authorElad, Sharon
dc.date.accessioned2021-11-23T03:32:42Z
dc.date.available2021-11-23T03:32:42Z
dc.date.issued2020-11-06
dc.identifier.citationMiranda-Silva, Wanessa, Gomes-Silva, Wagner, Zadik, Yehuda, Yarom, Noam, Al-Azri, Abdul Rahman, HSU LING CATHERINE HONG, Ariyawardana, Anura, Saunders, Deborah P, Correa, M Elvira, Arany, Praveen R, Bowen, Joanne, Cheng Kin Fong Karis, Tissing, Wim JE, Bossi, Paolo, Elad, Sharon (2020-11-06). MASCC/ISOO clinical practice guidelines for the management of mucositis: sub-analysis of current interventions for the management of oral mucositis in pediatric cancer patients. SUPPORTIVE CARE IN CANCER 29 (7) : 3539-3562. ScholarBank@NUS Repository. https://doi.org/10.1007/s00520-020-05803-4
dc.identifier.issn0941-4355
dc.identifier.issn1433-7339
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/207316
dc.description.abstractObjective: The aim of this sub-analysis was to highlight the MASCC/ISOO clinical practice guidelines for the management of oral mucositis (OM) in pediatric patients and to present unique considerations in this patient population. Methods: This sub-analysis of the pediatric patient population is based on the systematic review conducted by the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISSO) published in 2019/2020. Studies were scored and assigned a level of evidence based on previously published criteria. Data regarding adverse effects and compliance was collected from the original publications. Results: A total of 45 papers were included and assessed in this sub-analysis, including 21 randomized controlled trials (RCTs). Chewing gum was demonstrated to be not effective in preventing OM in pediatric cancer patients in 2 RCTs. The efficacy of all other interventions could not be determined based on the available literature. Conclusion: There is limited or conflicting evidence about interventions for the management of OM in pediatric cancer patients, except for chewing gum which was ineffective for prevention. Therefore, currently, data from adult studies may need to be extrapolated for the management of pediatric patients. Honey and photobiomodulation therapy in this patient population had encouraging potential. Implementation of a basic oral care protocol is advised amid lack of high level of evidence studies.
dc.language.isoen
dc.publisherSPRINGER
dc.sourceElements
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectOncology
dc.subjectHealth Care Sciences & Services
dc.subjectRehabilitation
dc.subjectCancer
dc.subjectPrevention
dc.subjectTreatment
dc.subjectOral mucositis
dc.subjectPain
dc.subjectPediatric patients
dc.subjectEvidence-based
dc.subjectGuidelines
dc.subjectSTEM-CELL TRANSPLANTATION
dc.subjectCOLONY-STIMULATING FACTOR
dc.subjectACUTE LYMPHOBLASTIC-LEUKEMIA
dc.subjectLEVEL LASER THERAPY
dc.subjectDOUBLE-BLIND
dc.subjectCONTROLLED ANALGESIA
dc.subjectGLUTAMINE SUPPLEMENTATION
dc.subjectVIRIDANS STREPTOCOCCI
dc.subjectYOUNG-PATIENTS
dc.subjectCHEWING GUM
dc.typeArticle
dc.date.updated2021-11-19T06:51:45Z
dc.contributor.departmentALICE LEE CENTRE FOR NURSING STUDIES
dc.contributor.departmentDEAN'S OFFICE (DENTISTRY)
dc.description.doi10.1007/s00520-020-05803-4
dc.description.sourcetitleSUPPORTIVE CARE IN CANCER
dc.description.volume29
dc.description.issue7
dc.description.page3539-3562
dc.published.statePublished
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