Please use this identifier to cite or link to this item: https://doi.org/10.1155/2014/984082
Title: Fluid resuscitation in sepsis: Reexamining the paradigm
Authors: Madhusudan, P
Vijayaraghavan, B.K.T
Cove, M.E 
Keywords: albumin
hetastarch
Ringer acetate
sodium chloride
abdominal compartment syndrome
adult respiratory distress syndrome
central venous pressure
colloid
crystalloid
fluid resuscitation
fluid therapy
heart output
human
intravenous drug administration
pH
pulmonary artery catheter
pulmonary artery occlusion pressure
Review
sepsis
septic shock
shock
venous congestion
venous oxygen tension
algorithm
complication
evidence based medicine
pathophysiology
procedures
resuscitation
sepsis
treatment outcome
Water-Electrolyte Imbalance
Algorithms
Evidence-Based Medicine
Fluid Therapy
Humans
Resuscitation
Sepsis
Treatment Outcome
Water-Electrolyte Imbalance
Issue Date: 2014
Citation: Madhusudan, P, Vijayaraghavan, B.K.T, Cove, M.E (2014). Fluid resuscitation in sepsis: Reexamining the paradigm. BioMed Research International 2014 : 984082. ScholarBank@NUS Repository. https://doi.org/10.1155/2014/984082
Rights: Attribution 4.0 International
Abstract: Sepsis results in widespread inflammatory responses altering homeostasis. Associated circulatory abnormalities (peripheral vasodilation, intravascular volume depletion, increased cellular metabolism, and myocardial depression) lead to an imbalance between oxygen delivery and demand, triggering end organ injury and failure. Fluid resuscitation is a key part of treatment, but there is little agreement on choice, amount, and end points for fluid resuscitation. Over the past few years, the safety of some fluid preparations has been questioned. Our paper highlights current concerns, reviews the science behind current practices, and aims to clarify some of the controversies surrounding fluid resuscitation in sepsis. Copyright © 2014 Poorna Madhusudan et al.
Source Title: BioMed Research International
URI: https://scholarbank.nus.edu.sg/handle/10635/183708
ISSN: 23146133
DOI: 10.1155/2014/984082
Rights: Attribution 4.0 International
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