Please use this identifier to cite or link to this item:
https://doi.org/10.3390/ijms17060940
| Title: | Hepatitis B virus X protein and hepatocarcinogenesis | Authors: | Liu, S Koh, S.S.Y Lee, C.G.L |
Keywords: | alpha fetoprotein chemokine receptor CXCR4 hepatitis B virus X protein long untranslated RNA mammalian target of rapamycin microRNA Notch receptor phosphatidylinositol 3 kinase phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase protein bcl 2 Ras protein reactive oxygen metabolite secreted frizzled related protein 1 secreted frizzled related protein 5 somatomedin B somatomedin binding protein 3 toll like receptor 3 tumor necrosis factor related apoptosis inducing ligand untranslated RNA hepatitis B virus X protein transactivator protein acetylation apoptosis chronic hepatitis B DNA methylation DNA repair epigenetics gene expression gene mutation human immunity liver cell carcinoma nonhuman oxidative stress protein expression Review signal transduction animal genetic epigenesis genetics liver cell carcinoma liver tumor metabolism virology Animals Carcinoma, Hepatocellular Epigenesis, Genetic Humans Liver Neoplasms Signal Transduction Trans-Activators |
Issue Date: | 2016 | Citation: | Liu, S, Koh, S.S.Y, Lee, C.G.L (2016). Hepatitis B virus X protein and hepatocarcinogenesis. International Journal of Molecular Sciences 17 (6) : 940. ScholarBank@NUS Repository. https://doi.org/10.3390/ijms17060940 | Rights: | Attribution 4.0 International | Abstract: | Chronic hepatitis B virus (HBV) infection is one of the most associated factors in hepatocarcinogenesis. HBV is able to integrate into the host genome and encode the multi-functional hepatitis B virus x protein (HBx). Although the mechanism between HBx and carcinogenesis is still elusive, recent studies have shown that HBx was able to influence various signaling pathways, as well as epigenetic and genetic processes. This review will examine and summarize recent literature about HBx’s role in these various processes. © 2016 by the authors; licensee MDPI, Basel, Switzerland. | Source Title: | International Journal of Molecular Sciences | URI: | https://scholarbank.nus.edu.sg/handle/10635/183327 | ISSN: | 16616596 | DOI: | 10.3390/ijms17060940 | Rights: | Attribution 4.0 International |
| Appears in Collections: | Staff Publications Elements |
Show full item record
Files in This Item:
| File | Description | Size | Format | Access Settings | Version | |
|---|---|---|---|---|---|---|
| 10_3390_ijms17060940.pdf | 1.29 MB | Adobe PDF | OPEN | None | View/Download |
This item is licensed under a Creative Commons License
