Please use this identifier to cite or link to this item: https://doi.org/10.7554/eLife.03883
Title: Improving pandemic influenza risk assessment
Authors: Russell, C.A
Kasson, P.M
Donis, R.O
Riley, S
Dunbar, J
Rambaut, A
Asher, J
Burke, S
Davis, C.T
Garten, R.J
Gnanakaran, S
Hay, S.I
Herfst, S
Lewis, N.S
Lloyd-Smith, J.O
Macken, C.A
Maurer-Stroh, S 
Neuhaus, E
Parrish, C.R
Pepin, K.M
Shepard, S.S
Smith, D.L
Suarez, D.L
Trock, S.C
Widdowson, M.-A
George, D.B
Lipsitch, M
Bloom, J
Keywords: biological model
epidemiological monitoring
evolution
genetics
geography
human
Influenza A virus
Influenza, Human
nucleotide sequence
Pandemics
procedures
public health
risk assessment
virology
Base Sequence
Biological Evolution
Epidemiological Monitoring
Geography
Humans
Influenza A virus
Influenza, Human
Models, Biological
Pandemics
Public Health
Risk Assessment
Issue Date: 2014
Citation: Russell, C.A, Kasson, P.M, Donis, R.O, Riley, S, Dunbar, J, Rambaut, A, Asher, J, Burke, S, Davis, C.T, Garten, R.J, Gnanakaran, S, Hay, S.I, Herfst, S, Lewis, N.S, Lloyd-Smith, J.O, Macken, C.A, Maurer-Stroh, S, Neuhaus, E, Parrish, C.R, Pepin, K.M, Shepard, S.S, Smith, D.L, Suarez, D.L, Trock, S.C, Widdowson, M.-A, George, D.B, Lipsitch, M, Bloom, J (2014). Improving pandemic influenza risk assessment. eLife 3 : e03883. ScholarBank@NUS Repository. https://doi.org/10.7554/eLife.03883
Rights: Attribution 4.0 International
Abstract: Assessing the pandemic risk posed by specific non-human influenza A viruses is an important goal in public health research. As influenza virus genome sequencing becomes cheaper, faster, and more readily available, the ability to predict pandemic potential from sequence data could transform pandemic influenza risk assessment capabilities. However, the complexities of the relationships between virus genotype and phenotype make such predictions extremely difficult. The integration of experimental work, computational tool development, and analysis of evolutionary pathways, together with refinements to influenza surveillance, has the potential to transform our ability to assess the risks posed to humans by non-human influenza viruses and lead to improved pandemic preparedness and response.
Source Title: eLife
URI: https://scholarbank.nus.edu.sg/handle/10635/182037
ISSN: 2050084X
DOI: 10.7554/eLife.03883
Rights: Attribution 4.0 International
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