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https://doi.org/10.1186/1475-2875-10-113
| Title: | Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand | Authors: | Rijken, M.J Boel, M.E Russell, B Imwong, M Leimanis, M.L Phyo, A.P Muehlenbachs, A Lindegardh, N McGready, R Rénia, L Snounou, G Singhasivanon, P Nosten, F |
Keywords: | chloroquine deethylchloroquine dihydroartemisinin piperaquine primaquine antimalarial agent chloroquine protozoal DNA adult antimalarial drug susceptibility article case report female human parasitemia Plasmodium vivax Plasmodium vivax malaria polymerase chain reaction pregnancy Thailand drug effect drug resistance drug sensitivity genetics genotype isolation and purification parasitology Plasmodium vivax Plasmodium vivax malaria pregnancy complication Adult Antimalarials Chloroquine DNA, Protozoan Drug Resistance Female Genotype Humans Malaria, Vivax Parasitic Sensitivity Tests Plasmodium vivax Pregnancy Pregnancy Complications, Infectious Thailand |
Issue Date: | 2011 | Citation: | Rijken, M.J, Boel, M.E, Russell, B, Imwong, M, Leimanis, M.L, Phyo, A.P, Muehlenbachs, A, Lindegardh, N, McGready, R, Rénia, L, Snounou, G, Singhasivanon, P, Nosten, F (2011). Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand. Malaria Journal 10 : 113. ScholarBank@NUS Repository. https://doi.org/10.1186/1475-2875-10-113 | Rights: | Attribution 4.0 International | Abstract: | Chloroquine (CQ) resistant vivax malaria is spreading. In this case, Plasmodium vivax infections during pregnancy and in the postpartum period were not satisfactorily cleared by CQ, despite adequate drug concentrations. A growth restricted infant was delivered. Poor susceptibility to CQ was confirmed in-vitro and molecular genotyping was strongly suggestive of true recrudescence of P. vivax. This is the first clinically and laboratory confirmed case of two high-grade CQ resistant vivax parasite strains from Thailand. © 2011 Rijken et al; licensee BioMed Central Ltd. | Source Title: | Malaria Journal | URI: | https://scholarbank.nus.edu.sg/handle/10635/181636 | ISSN: | 14752875 | DOI: | 10.1186/1475-2875-10-113 | Rights: | Attribution 4.0 International |
| Appears in Collections: | Elements Staff Publications |
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