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Title: | Clinical laboratory practices for the detection of rotavirus in England and Wales: can surveillance based on routine laboratory testing data be used to evaluate the impact of vaccination? | Authors: | Atchison, C.J Lopman, B.A Harris, C.J Tam, C.C Iturriza Gómara, M Gray, J.J |
Keywords: | Rotavirus vaccine article diagnosis, measurement and analysis drug effect health care policy health survey human isolation and purification methodology preventive health service questionnaire Rotavirus treatment outcome United Kingdom virology virus infection England Health Policy Humans Immunization Programs Laboratory Techniques and Procedures Population Surveillance Questionnaires Rotavirus Rotavirus Infections Rotavirus Vaccines Treatment Outcome Wales |
Issue Date: | 2009 | Citation: | Atchison, C.J, Lopman, B.A, Harris, C.J, Tam, C.C, Iturriza Gómara, M, Gray, J.J (2009). Clinical laboratory practices for the detection of rotavirus in England and Wales: can surveillance based on routine laboratory testing data be used to evaluate the impact of vaccination?. Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin 14 (20). ScholarBank@NUS Repository. https://doi.org/10.2807/ese.14.20.19217-en | Rights: | Attribution 4.0 International | Abstract: | Two rotavirus vaccines have recently been licensed in Europe. Rotavirus surveillance data in many European countries are based on reports of laboratory-confirmed rotavirus infections. If surveillance data based on routine laboratory testing data are to be used to evaluate the impact of vaccination programmes, it is important to determine how the data are influenced by differences in testing practices, and how these practices are likely to affect the ability of the surveillance data to represent trends in rotavirus disease in the community. We conducted a survey of laboratory testing policies for rotavirus gastroenteritis in England and Wales in 2008. 60% (94/156) of laboratories responded to the survey. 91% of reporting laboratories offered routine testing for rotavirus all year round and 89% of laboratories offered routine rotavirus testing of all stool specimens from children under the age of five years. In 96% of laboratories, rotavirus detection was presently done either by rapid immunochromatographic tests or by enzyme-linked immunosorbent assay. Currently, rotavirus testing policies among laboratories in England and Wales are relatively homogenous. Therefore, surveillance based on laboratory testing data is likely to be representative of rotavirus disease trends in the community in the most frequently affected age groups (children under the age of five years) and could be used to help determine the impact of a rotavirus vaccine. | Source Title: | Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin | URI: | https://scholarbank.nus.edu.sg/handle/10635/177962 | ISSN: | 15607917 | DOI: | 10.2807/ese.14.20.19217-en | Rights: | Attribution 4.0 International |
Appears in Collections: | Elements Staff Publications |
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