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Title: Alternative technique of long acting cardioplegia delivery results in less hemodilution
Authors: Ong, Geok Seen
Guim, Goh Si
Lim, Qi Xuan
Chay-Nancy, Huang Shoo
Jaafar, Nurdiyana Binte 
Lim, Clara Anne
Clement, Chew Kai Hong
Sazzad, Faizus 
Kofidis, Theo
Keywords: Science & Technology
Life Sciences & Biomedicine
Cardiac & Cardiovascular Systems
Peripheral Vascular Disease
Cardiovascular System & Cardiology
cardiopulmonary bypass
Issue Date: 10-Aug-2020
Citation: Ong, Geok Seen, Guim, Goh Si, Lim, Qi Xuan, Chay-Nancy, Huang Shoo, Jaafar, Nurdiyana Binte, Lim, Clara Anne, Clement, Chew Kai Hong, Sazzad, Faizus, Kofidis, Theo (2020-08-10). Alternative technique of long acting cardioplegia delivery results in less hemodilution. PERFUSION-UK. ScholarBank@NUS Repository.
Abstract: © The Author(s) 2020. Background: Preparation of del-Nido cardioplegia and its delivery technique can cause significant hemodilution. The resultant effects from hemodilution are largely proportionate to the use of a dual circuit. We opted for a custom-disposable single cardioplegia circuit instead of a dual circuit. Methods: We describe an alternative technique of del-Nido cardioplegia delivery and initial clinical experience with it at National University Hospital, Singapore. This is a retrospective analysis of data from January 2017 to April 2019, comprising of 177 patients of heart surgery and reflecting a single center database survey under the National Health Care Group. Results: Of the 177 patients who underwent surgery with del-Nido cardioplegia, 76 (42.9%) were valve-only procedures and 5 (2.8%) were coronary artery bypass graft–only procedures. Ultrafiltration was utilized in 132 (62.6%) patients, whereas filtrate volume was 2200 [150-9500] mL. The alternative technique of del-Nido cardioplegia delivery adopted by National University Hospital advocates for a single pump, single circuit system. The retrospective institutional data highlighted safe delivery of del-Nido cardioplegia using this technique in a range of procedures. Conclusion: Besides the safe delivery of del-Nido cardioplegia, the National University Hospital Technique reduces hemodilution and provides other technical benefits including a steeper temperature gradient, modification of circuit configuration to deliver another cardioplegia while on bypass, as well as re-configuration of clamps to spike the base solution.
Source Title: PERFUSION-UK
ISSN: 02676591
DOI: 10.1177/0267659120946727
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