Please use this identifier to cite or link to this item: https://doi.org/10.1039/c6ra11289g
Title: Nanomaterial mediated optogenetics: Opportunities and challenges
Authors: Huang, K 
Dou, Q
Loh, X.J 
Keywords: Neurons
Excitation light
Invasiveness
Light delivery systems
Modulation strategy
Moving animals
Neural activity
Neuromodulation
Spatiotemporal control
Nanostructured materials
Issue Date: 2016
Citation: Huang, K, Dou, Q, Loh, X.J (2016). Nanomaterial mediated optogenetics: Opportunities and challenges. RSC Advances 6 (65) : 60896-60906. ScholarBank@NUS Repository. https://doi.org/10.1039/c6ra11289g
Abstract: Optogenetics is a promising neuronal modulation strategy in neuroscience, which enables real-time neuromodulation in free-moving animals with high spatiotemporal control. However, it still suffers from several disadvantages, including low penetration of excitation light and the invasiveness of the insertion of the light delivery system. The incorporation of nanomaterials with different properties into optogenetics may bring new opportunities to solve the problems encountered in optogenetics, from the delivery/expression of the optogene to the stimulation/inhibition and follow-up sensing of neural activity. The challenges of nanomaterial-mediated optogenetics are also discussed. This review elaborates on the feasibility of incorporating nanomaterials into optogenetics and analyzes the benefits of nanomaterial-mediated optogenetics. © 2016 The Royal Society of Chemistry.
Source Title: RSC Advances
URI: https://scholarbank.nus.edu.sg/handle/10635/175967
ISSN: 2046-2069
DOI: 10.1039/c6ra11289g
Appears in Collections:Elements
Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1039_c6ra11289g.pdf888.45 kBAdobe PDF

OPEN

NoneView/Download

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.