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Please use this identifier to cite or link to this item: https://doi.org/10.1039/c6ra11289g
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dc.titleNanomaterial mediated optogenetics: Opportunities and challenges
dc.contributor.authorHuang, K
dc.contributor.authorDou, Q
dc.contributor.authorLoh, X.J
dc.date.accessioned2020-09-14T07:33:26Z
dc.date.available2020-09-14T07:33:26Z
dc.date.issued2016
dc.identifier.citationHuang, K, Dou, Q, Loh, X.J (2016). Nanomaterial mediated optogenetics: Opportunities and challenges. RSC Advances 6 (65) : 60896-60906. ScholarBank@NUS Repository. https://doi.org/10.1039/c6ra11289g
dc.identifier.issn2046-2069
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/175967
dc.description.abstractOptogenetics is a promising neuronal modulation strategy in neuroscience, which enables real-time neuromodulation in free-moving animals with high spatiotemporal control. However, it still suffers from several disadvantages, including low penetration of excitation light and the invasiveness of the insertion of the light delivery system. The incorporation of nanomaterials with different properties into optogenetics may bring new opportunities to solve the problems encountered in optogenetics, from the delivery/expression of the optogene to the stimulation/inhibition and follow-up sensing of neural activity. The challenges of nanomaterial-mediated optogenetics are also discussed. This review elaborates on the feasibility of incorporating nanomaterials into optogenetics and analyzes the benefits of nanomaterial-mediated optogenetics. © 2016 The Royal Society of Chemistry.
dc.sourceUnpaywall 20200831
dc.subjectNeurons
dc.subjectExcitation light
dc.subjectInvasiveness
dc.subjectLight delivery systems
dc.subjectModulation strategy
dc.subjectMoving animals
dc.subjectNeural activity
dc.subjectNeuromodulation
dc.subjectSpatiotemporal control
dc.subjectNanostructured materials
dc.typeArticle
dc.contributor.departmentBIOMEDICAL ENGINEERING
dc.contributor.departmentMATERIALS SCIENCE AND ENGINEERING
dc.description.doi10.1039/c6ra11289g
dc.description.sourcetitleRSC Advances
dc.description.volume6
dc.description.issue65
dc.description.page60896-60906
dc.published.statePublished
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