Please use this identifier to cite or link to this item: https://doi.org/10.1038/ncomms9832
Title: Subwavelength imaging through ion-beam-induced upconversion
Authors: Mi, Z 
Zhang, Y
Vanga, S.K 
Chen, C.-B 
Tan, H.Q
Watt, F 
Liu, X 
Bettiol, A.A 
Keywords: lanthanide
nanocrystal
crystal structure
diffraction
dye
imaging method
luminescence
microscopy
probe
rare earth element
spatial resolution
wavelength
Article
bleaching
cell structure
crystal
energy transfer
infrared radiation
ion beam induced upconversion
ion therapy
luminescence
optical resolution
scanning electron microscopy
subwavelength imaging
Issue Date: 2015
Publisher: Nature Publishing Group
Citation: Mi, Z, Zhang, Y, Vanga, S.K, Chen, C.-B, Tan, H.Q, Watt, F, Liu, X, Bettiol, A.A (2015). Subwavelength imaging through ion-beam-induced upconversion. Nature Communications 6 : 8832. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms9832
Abstract: The combination of an optical microscope and a luminescent probe plays a pivotal role in biological imaging because it allows for probing subcellular structures. However, the optical resolutions are largely constrained by Abbe's diffraction limit, and the common dye probes often suffer from photobleaching. Here we present a new method for subwavelength imaging by combining lanthanide-doped upconversion nanocrystals with the ionoluminescence imaging technique. We experimentally observed that the ion beam can be used as a new form of excitation source to induce photon upconversion in lanthanide-doped nanocrystals. This approach enables luminescence imaging and simultaneous mapping of cellular structures with a spatial resolution of sub-30nm. © 2015 Macmillan Publishers Limited. All rights reserved.
Source Title: Nature Communications
URI: https://scholarbank.nus.edu.sg/handle/10635/175466
ISSN: 20411723
DOI: 10.1038/ncomms9832
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1038_ncomms9832.pdf1.52 MBAdobe PDF

OPEN

NoneView/Download

SCOPUSTM   
Citations

19
checked on Nov 18, 2020

Page view(s)

16
checked on Nov 19, 2020

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.