Please use this identifier to cite or link to this item: https://doi.org/10.1186/s12880-018-0270-8
Title: A pilot study on adjunctive use of parametric colour-coded digital subtraction angiography in endovascular interventions of haemodialysis access
Authors: Tan, R.Y
Chong, T.T 
Tsai, F.C
Pang, S.C
Lee, K.G
Gogna, A 
Ong, A.H
Tan, C.S 
Keywords: aged
angioplasty
color
comparative study
digital subtraction angiography
feasibility study
female
hemodialysis
human
male
middle aged
pilot study
procedures
retrospective study
Aged
Angiography, Digital Subtraction
Angioplasty
Color
Feasibility Studies
Female
Humans
Male
Middle Aged
Pilot Projects
Renal Dialysis
Retrospective Studies
Issue Date: 2018
Citation: Tan, R.Y, Chong, T.T, Tsai, F.C, Pang, S.C, Lee, K.G, Gogna, A, Ong, A.H, Tan, C.S (2018). A pilot study on adjunctive use of parametric colour-coded digital subtraction angiography in endovascular interventions of haemodialysis access. BMC Medical Imaging 18 (1) : 28. ScholarBank@NUS Repository. https://doi.org/10.1186/s12880-018-0270-8
Abstract: Background: Two-dimensional digital subtraction angiography (DSA) is the gold standard for angiographic evaluation of dysfunctional haemodialysis access. We aim to investigate the utility of parametric colour coded DSA in providing hemodynamic analysis during haemodialysis access interventions. Methods: We retrospectively studied 20 patients who underwent access intervention and applied parametric colour-coding on selected DSA acquisitions before and after percutaneous transluminal angioplasty (PTA). The difference in time to peak (dTTP) contrast enhancement and time attenuation curve (TAC) of pre- and post-stenotic regions of interest (ROIs) were obtained and compared after treatment. Results: Improvements were seen in mean percent of stenosis after PTA (p<0.0001) for all cases. Median dTTP improved from 0.52 (IQR 0.26, 0.8) to 0.25 (IQR 0, 0.26) seconds (p=0.001). Median 50% contrast washout time improved from 0.77 (IQR 0.39, 1.17) to 0.42 (IQR 0.23, 0.59) seconds (p=0.031). Significant correlation was seen for dTTP vs. percent of stenosis (r=0.723, p=0.043) pre-PTA and for change in dTTP vs. percent change in stenosis post-PTA (r=0.786, p=0.021) for inflow lesions. Such correlation was however not seen in outflow lesions. Conclusions: Adjunctive use of parametric colour-coded DSA may provide potentially useful hemodynamic information during vascular access interventions. Larger prospective studies are needed to validate our findings. © 2018 The Author(s).
Source Title: BMC Medical Imaging
URI: https://scholarbank.nus.edu.sg/handle/10635/175367
ISSN: 1471-2342
DOI: 10.1186/s12880-018-0270-8
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