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https://doi.org/10.1186/s40793-017-0247-1
| Title: | Genomics insights into production of 2-methylisoborneol and a putative cyanobactin by Planktothricoides sp. SR001 | Authors: | Te S.H. Tan B.F. Boo C.Y. Thompson J.R. Gin K.Y.-H. |
Keywords: | 2 methylisoborneol contig cyanobactin RNA 16S tripeptide unclassified drug Article bacterial gene bacterial genome bacterial overgrowth bacterium examination bioinformatics clustered regularly interspaced short palindromic repeat cyanobacterium DNA base composition gene function genome analysis genome size molecular genetics nonhuman Planktothricoides pseudogene RNA gene RNA sequence sequence alignment |
Issue Date: | 2017 | Citation: | Te S.H., Tan B.F., Boo C.Y., Thompson J.R., Gin K.Y.-H. (2017). Genomics insights into production of 2-methylisoborneol and a putative cyanobactin by Planktothricoides sp. SR001. Standards in Genomic Sciences 12 (1) : 35. ScholarBank@NUS Repository. https://doi.org/10.1186/s40793-017-0247-1 | Abstract: | Planktothricoides is a free-living filamentous cyanobacterium belonging to the order Oscillatoriales and the family Phormidiaceae, capable of forming bloom in fresh and brackish waters. A unicyanobacterial non-axenic culture dominated by Planktothricoides sp. SR001 was obtained from a freshwater reservoir in Singapore. The draft genome presented here is the first tropical freshwater Planktothricoides sp. ever sequenced. The genome of 7.0Mbp contains 5,776 genes predicted using the JGI IMG pipeline. The whole genome sequence allows identification of genes encoding for nitrogen-fixation, accessory photosynthetic pigments and biosynthesis of an off-flavor compound, 2-methylisoborneol, which has been experimentally verified here based on metabolite detection. In addition, strain SR001 genome contains an operon putatively involved in the production of a linear tripeptide cyanobactin related to viridisamide A and aeruginosamide, with the later known to possess anti-microbial or cytotoxic effect. © 2017 The Author(s). | Source Title: | Standards in Genomic Sciences | URI: | https://scholarbank.nus.edu.sg/handle/10635/173786 | ISSN: | 19443277 | DOI: | 10.1186/s40793-017-0247-1 |
| Appears in Collections: | Staff Publications Elements |
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