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https://doi.org/10.1039/c9qo00471h
Title: | Creation of bispiro[pyrazolone-3,3 '-oxindoles] via a phosphine-catalyzed enantioselective [3+2] annulation of the Morita-Baylis-Hillman carbonates with pyrazoloneyldiene oxindoles | Authors: | Zhang, Jing Chan, Wai-Lun Chen, Ligong Ullah, Nisar Lu, Yixin |
Keywords: | Science & Technology Physical Sciences Chemistry, Organic Chemistry MICHAEL ADDITION CONSTRUCTION CASCADE ALLENES SPIROOXINDOLES ALLENOATES DISCOVERY KETIMINES DESIGN POTENT |
Issue Date: | 7-Jul-2019 | Publisher: | ROYAL SOC CHEMISTRY | Citation: | Zhang, Jing, Chan, Wai-Lun, Chen, Ligong, Ullah, Nisar, Lu, Yixin (2019-07-07). Creation of bispiro[pyrazolone-3,3 '-oxindoles] via a phosphine-catalyzed enantioselective [3+2] annulation of the Morita-Baylis-Hillman carbonates with pyrazoloneyldiene oxindoles. ORGANIC CHEMISTRY FRONTIERS 6 (13) : 2210-2214. ScholarBank@NUS Repository. https://doi.org/10.1039/c9qo00471h | Abstract: | © the Partner Organisations 2019. A [3 + 2] annulation between the Morita-Baylis-Hillman (MBH) carbonates and pyrazoloneyldiene oxindoles catalyzed by (S)-SITCP has been developed. Structurally novel bispiro[pyrazolone-3,3′-oxindoles] containing two contiguous quaternary stereogenic centers were created in excellent yields, in a diastereospecific and highly enantioselective manner. | Source Title: | ORGANIC CHEMISTRY FRONTIERS | URI: | https://scholarbank.nus.edu.sg/handle/10635/169692 | ISSN: | 20524129 | DOI: | 10.1039/c9qo00471h |
Appears in Collections: | Staff Publications Elements |
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[2] QO-RES-04-2019-000471_ revised Yixin LU.docx | 6.43 MB | Microsoft Word XML | OPEN | Post-print | View/Download |
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