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https://doi.org/10.1371/journal.pone.0140129
Title: | Impact of regional vein thrombosis in patients with Klebsiella pneumoniae liver abscess | Authors: | Molton J.S. Chee Y.L. Hennedige T.P. Venkatesh S.K. Archuleta S. |
Keywords: | abscess drainage adult age Article computer assisted tomography controlled study deep vein thrombosis diabetes mellitus disease association female gender human immobility inferior vena cava thrombosis Klebsiella pneumoniae Klebsiella pneumoniae infection liver abscess liver vein thrombosis lung embolism major clinical study male portal vein thrombosis retrospective study thrombophlebitis complication isolation and purification Klebsiella infection liver abscess liver vein microbiology middle aged pathology thrombophlebitis anticoagulant agent Anticoagulants Female Hepatic Veins Humans Klebsiella Infections Klebsiella pneumoniae Liver Abscess Male Middle Aged Retrospective Studies Thrombophlebitis |
Issue Date: | 2015 | Citation: | Molton J.S., Chee Y.L., Hennedige T.P., Venkatesh S.K., Archuleta S. (2015). Impact of regional vein thrombosis in patients with Klebsiella pneumoniae liver abscess. PLoS ONE 10 (10) : e0140129. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0140129 | Rights: | Attribution 4.0 International | Abstract: | Klebsiella liver abscess (KLA) is an emerging infection in Asia caused by hypermucoviscous strains of Klebsiella pneumoniae. It is associated with thrombophlebitis of portal and hepatic veins. The natural history and role of anticoagulation for this regional thrombophlebitis is unclear. In a retrospective study of 169 subjects with KLA over 7 years, thrombophlebitis was identified in 53/169 (31.4%). Only 1 received therapeutic anticoagulation. Despite this 30/49 (73.2%) of those with follow up scan available showed improvement or recanalization (mean duration between scans 44 days). Abscess resolution was associated with improvement in thrombophlebitis. Copyright: © 2015 Molton et al. | Source Title: | PLoS ONE | URI: | https://scholarbank.nus.edu.sg/handle/10635/161487 | ISSN: | 19326203 | DOI: | 10.1371/journal.pone.0140129 | Rights: | Attribution 4.0 International |
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