Please use this identifier to cite or link to this item: https://doi.org/10.1371/journal.pone.0140129
Title: Impact of regional vein thrombosis in patients with Klebsiella pneumoniae liver abscess
Authors: Molton J.S. 
Chee Y.L. 
Hennedige T.P. 
Venkatesh S.K.
Archuleta S. 
Keywords: abscess drainage
adult
age
Article
computer assisted tomography
controlled study
deep vein thrombosis
diabetes mellitus
disease association
female
gender
human
immobility
inferior vena cava thrombosis
Klebsiella pneumoniae
Klebsiella pneumoniae infection
liver abscess
liver vein thrombosis
lung embolism
major clinical study
male
portal vein thrombosis
retrospective study
thrombophlebitis
complication
isolation and purification
Klebsiella infection
liver abscess
liver vein
microbiology
middle aged
pathology
thrombophlebitis
anticoagulant agent
Anticoagulants
Female
Hepatic Veins
Humans
Klebsiella Infections
Klebsiella pneumoniae
Liver Abscess
Male
Middle Aged
Retrospective Studies
Thrombophlebitis
Issue Date: 2015
Citation: Molton J.S., Chee Y.L., Hennedige T.P., Venkatesh S.K., Archuleta S. (2015). Impact of regional vein thrombosis in patients with Klebsiella pneumoniae liver abscess. PLoS ONE 10 (10) : e0140129. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0140129
Abstract: Klebsiella liver abscess (KLA) is an emerging infection in Asia caused by hypermucoviscous strains of Klebsiella pneumoniae. It is associated with thrombophlebitis of portal and hepatic veins. The natural history and role of anticoagulation for this regional thrombophlebitis is unclear. In a retrospective study of 169 subjects with KLA over 7 years, thrombophlebitis was identified in 53/169 (31.4%). Only 1 received therapeutic anticoagulation. Despite this 30/49 (73.2%) of those with follow up scan available showed improvement or recanalization (mean duration between scans 44 days). Abscess resolution was associated with improvement in thrombophlebitis. Copyright: © 2015 Molton et al.
Source Title: PLoS ONE
URI: https://scholarbank.nus.edu.sg/handle/10635/161487
ISSN: 19326203
DOI: 10.1371/journal.pone.0140129
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