Please use this identifier to cite or link to this item: https://doi.org/10.1371/journal.pone.0175080
Title: Phylogeography of Y-chromosome haplogroup O3a2b2-N6 reveals patrilineal traces of Austronesian populations on the eastern coastal regions of Asia
Authors: Wei L.-H.
Yan S.
Teo Y.-Y.
Huang Y.-Z.
Wang L.-X.
Yu G.
Saw W.-Y. 
Ong R.T.-H. 
Lu Y.
Zhang C.
Xu S.-H.
Jin L.
Li H.
Keywords: China
chromosome polymorphism
clinical article
diffusion
foxtail millet
human
Korea
nonhuman
phylogenetic tree
phylogeography
Viet Nam
Y chromosome haplogroup
Asian continental ancestry group
China
genetic polymorphism
genetics
genotyping technique
haplotype
history
male
migration
Oceanic ancestry group
phylogeography
Y chromosome
Asian Continental Ancestry Group
China
Chromosomes, Human, Y
Genotyping Techniques
Haplotypes
History, Ancient
Human Migration
Humans
Korea
Male
Oceanic Ancestry Group
Phylogeography
Polymorphism, Genetic
Vietnam
Issue Date: 2017
Citation: Wei L.-H., Yan S., Teo Y.-Y., Huang Y.-Z., Wang L.-X., Yu G., Saw W.-Y., Ong R.T.-H., Lu Y., Zhang C., Xu S.-H., Jin L., Li H. (2017). Phylogeography of Y-chromosome haplogroup O3a2b2-N6 reveals patrilineal traces of Austronesian populations on the eastern coastal regions of Asia. PLoS ONE 12 (4) : e0175080. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0175080
Rights: Attribution 4.0 International
Abstract: Austronesian diffusion is considered one of the greatest dispersals in human history; it led to the peopling of an extremely vast region, ranging from Madagascar in the Indian Ocean to Easter Island in Remote Oceania. The Y-chromosome haplogroup O3a2b?-P164(xM134), a predominant paternal lineage of Austronesian populations, is found at high frequencies in Polynesian populations. However, the internal phylogeny of this haplogroup remains poorly investigated. In this study, we analyzed -seventeen Y-chromosome sequences of haplogroup O3a2b?-P164(xM134) and generated a revised phylogenetic tree of this lineage based on 310 non-private Y-chromosome polymorphisms. We discovered that all available O3a2b?-P164(xM134) samples belong to the newly defined haplogroup O3a2b2-N6 and samples from Austronesian populations belong to the sublineage O3a2b2a2-F706. Additionally, we genotyped a series of Y-chromosome polymorphisms in a large collection of samples from China. We confirmed that the sublineage O3a2b2a2b-B451 is unique to Austronesian populations. We found that O3a2b2-N6 samples are widely distributed on the eastern coastal regions of Asia, from Korea to Vietnam. Furthermore, we propose- that the O3a2b2a2b-B451 lineage represents a genetic connection between ancestors of Austronesian populations and ancient populations in North China, where foxtail millet was domesticated about 11,000 years ago. The large number of newly defined Y-chromosome polymorphisms and the revised phylogenetic tree of O3a2b2-N6 will be helpful to explore the origin of proto-Austronesians and the early diffusion process of Austronesian populations. © 2017 Wei et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Source Title: PLoS ONE
URI: https://scholarbank.nus.edu.sg/handle/10635/161198
ISSN: 19326203
DOI: 10.1371/journal.pone.0175080
Rights: Attribution 4.0 International
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