Please use this identifier to cite or link to this item: https://doi.org/10.1093/nar/gkv1123
Title: NCG 5.0: Updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings
Authors: An, O 
Dall'Olio, GM
Mourikis, TP
Ciccarelli, FD
Keywords: Data Curation
Databases, Genetic
Genes, Neoplasm
Humans
Molecular Sequence Annotation
Mutation
Neoplasms
Issue Date: 1-Jan-2016
Publisher: Oxford University Press (OUP)
Citation: An, O, Dall'Olio, GM, Mourikis, TP, Ciccarelli, FD (2016-01-01). NCG 5.0: Updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings. Nucleic Acids Research 44 (D1) : D992-D999. ScholarBank@NUS Repository. https://doi.org/10.1093/nar/gkv1123
Abstract: © The Author(s) 2015. The Network of Cancer Genes (NCG, http://ncg.kcl. ac.UK/) is a manually curated repository of cancer genes derived from the scientific literature. Due to the increasing amount of cancer genomic data, we have introduced a more robust procedure to extract cancer genes frompublished cancer mutational screenings and two curators independently reviewed each publication. NCG release 5.0 (August 2015) collects 1571 cancer genes from 175 published studies that describe 188 mutational screenings of 13 315 cancer samples from 49 cancer types and 24 primary sites. In addition to collecting cancer genes, NCG also provides information on the experimental validation that supports the role of these genes in cancer and annotates their properties (duplicability, evolutionary origin, expression profile, function and interactions with proteins and miRNAs).
Source Title: Nucleic Acids Research
URI: https://scholarbank.nus.edu.sg/handle/10635/155278
ISSN: 0305-1048
1362-4962
DOI: 10.1093/nar/gkv1123
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