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Please use this identifier to cite or link to this item: https://doi.org/10.1093/nar/gkv1123
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dc.titleNCG 5.0: Updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings
dc.contributor.authorAn, O
dc.contributor.authorDall'Olio, GM
dc.contributor.authorMourikis, TP
dc.contributor.authorCiccarelli, FD
dc.date.accessioned2019-06-07T01:35:42Z
dc.date.available2019-06-07T01:35:42Z
dc.date.issued2016-01-01
dc.identifier.citationAn, O, Dall'Olio, GM, Mourikis, TP, Ciccarelli, FD (2016-01-01). NCG 5.0: Updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings. Nucleic Acids Research 44 (D1) : D992-D999. ScholarBank@NUS Repository. https://doi.org/10.1093/nar/gkv1123
dc.identifier.issn0305-1048
dc.identifier.issn1362-4962
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/155278
dc.description.abstract© The Author(s) 2015. The Network of Cancer Genes (NCG, http://ncg.kcl. ac.UK/) is a manually curated repository of cancer genes derived from the scientific literature. Due to the increasing amount of cancer genomic data, we have introduced a more robust procedure to extract cancer genes frompublished cancer mutational screenings and two curators independently reviewed each publication. NCG release 5.0 (August 2015) collects 1571 cancer genes from 175 published studies that describe 188 mutational screenings of 13 315 cancer samples from 49 cancer types and 24 primary sites. In addition to collecting cancer genes, NCG also provides information on the experimental validation that supports the role of these genes in cancer and annotates their properties (duplicability, evolutionary origin, expression profile, function and interactions with proteins and miRNAs).
dc.publisherOxford University Press (OUP)
dc.sourceElements
dc.subjectData Curation
dc.subjectDatabases, Genetic
dc.subjectGenes, Neoplasm
dc.subjectHumans
dc.subjectMolecular Sequence Annotation
dc.subjectMutation
dc.subjectNeoplasms
dc.typeArticle
dc.date.updated2019-06-03T09:38:50Z
dc.contributor.departmentCANCER SCIENCE INSTITUTE OF SINGAPORE
dc.description.doi10.1093/nar/gkv1123
dc.description.sourcetitleNucleic Acids Research
dc.description.volume44
dc.description.issueD1
dc.description.pageD992-D999
dc.published.statePublished
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