Please use this identifier to cite or link to this item:
Title: Alpha-synuclein haplotypes implicated in risk of Parkinson's disease
Authors: Tan E.-K. 
Chai A.
Teo Y.Y. 
Zhao Y.
Tan C.
Shen H.
Chandran V.R.
Teoh M.L.
Yih Y.
Pavanni R. 
Wong M.C. 
Puvan K. 
Lo Y.L. 
Yap E. 
Issue Date: 2004
Publisher: Lippincott Williams and Wilkins
Citation: Tan E.-K., Chai A., Teo Y.Y., Zhao Y., Tan C., Shen H., Chandran V.R., Teoh M.L., Yih Y., Pavanni R., Wong M.C., Puvan K., Lo Y.L., Yap E. (2004). Alpha-synuclein haplotypes implicated in risk of Parkinson's disease. Neurology 62 (1) : 128-131. ScholarBank@NUS Repository.
Abstract: The authors examined four- and six-loci haplotype constructs (from five single nucleotide polymorphisms and three microsatellite regions) of the alpha-synuclein gene in patients with Parkinson's disease (PD) and controls in an ethnic Chinese population. Logistic regression analysis demonstrated an association of NACP-Rep1 (p = 0.002) and L478 (p < 0.0001) with risk of PD after correction for the effects of age, sex, and the other polymorphic loci. Specific four-loci and six-loci haplotypes were significantly associated with an increased or decreased risk of PD.
Source Title: Neurology
ISSN: 00283878
DOI: 10.1212/01.WNL.0000101721.25345.DC
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.