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Please use this identifier to cite or link to this item: https://doi.org/10.1212/01.WNL.0000101721.25345.DC
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dc.titleAlpha-synuclein haplotypes implicated in risk of Parkinson's disease
dc.contributor.authorTan E.-K.
dc.contributor.authorChai A.
dc.contributor.authorTeo Y.Y.
dc.contributor.authorZhao Y.
dc.contributor.authorTan C.
dc.contributor.authorShen H.
dc.contributor.authorChandran V.R.
dc.contributor.authorTeoh M.L.
dc.contributor.authorYih Y.
dc.contributor.authorPavanni R.
dc.contributor.authorWong M.C.
dc.contributor.authorPuvan K.
dc.contributor.authorLo Y.L.
dc.contributor.authorYap E.
dc.date.accessioned2018-12-27T06:33:11Z
dc.date.available2018-12-27T06:33:11Z
dc.date.issued2004
dc.identifier.citationTan E.-K., Chai A., Teo Y.Y., Zhao Y., Tan C., Shen H., Chandran V.R., Teoh M.L., Yih Y., Pavanni R., Wong M.C., Puvan K., Lo Y.L., Yap E. (2004). Alpha-synuclein haplotypes implicated in risk of Parkinson's disease. Neurology 62 (1) : 128-131. ScholarBank@NUS Repository. https://doi.org/10.1212/01.WNL.0000101721.25345.DC
dc.identifier.issn00283878
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/150238
dc.description.abstractThe authors examined four- and six-loci haplotype constructs (from five single nucleotide polymorphisms and three microsatellite regions) of the alpha-synuclein gene in patients with Parkinson's disease (PD) and controls in an ethnic Chinese population. Logistic regression analysis demonstrated an association of NACP-Rep1 (p = 0.002) and L478 (p < 0.0001) with risk of PD after correction for the effects of age, sex, and the other polymorphic loci. Specific four-loci and six-loci haplotypes were significantly associated with an increased or decreased risk of PD.
dc.publisherLippincott Williams and Wilkins
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.contributor.departmentSAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
dc.contributor.departmentPHARMACOLOGY
dc.description.doi10.1212/01.WNL.0000101721.25345.DC
dc.description.sourcetitleNeurology
dc.description.volume62
dc.description.issue1
dc.description.page128-131
dc.published.statepublished
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