Please use this identifier to cite or link to this item:
|Title:||Inflammatory lymphangiogenesis: Cellular mediators and functional implications||Authors:||Tan, K.W.
Fibroblastic reticular cells
|Issue Date:||1-Apr-2014||Citation:||Tan, K.W., Chong, S.Z., Angeli, V. (2014-04-01). Inflammatory lymphangiogenesis: Cellular mediators and functional implications. Angiogenesis 17 (2) : 373-381. ScholarBank@NUS Repository. https://doi.org/10.1007/s10456-014-9419-4||Abstract:||In adult mammals, lymphatic vessels have been shown to respond to their environment by undergoing lymphangiogenesis, the formation of new lymphatic vessels from preexisting ones. Accumulating experimental and preclinical studies demonstrate that lymphangiogenesis is associated with many inflammatory diseases and may represent an attractive therapeutic target for inflammatory diseases. Thus, a better understanding of how lymphangiogenesis is regulated and contribution to inflammation is critical and may benefit clinical research targeting chronic inflammatory diseases. This review discusses the biological functions of lymphangiogenesis during inflammation and our current understanding of the key cellular players that can either support or limit lymphangiogenesis. Current data suggest that the context and time frame in which lymphangiogenesis occurs will determine its impact on the course of inflammation. © 2014 Springer Science+Business Media Dordrecht.||Source Title:||Angiogenesis||URI:||http://scholarbank.nus.edu.sg/handle/10635/126732||ISSN:||15737209||DOI:||10.1007/s10456-014-9419-4|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on May 16, 2019
WEB OF SCIENCETM
checked on May 8, 2019
checked on May 14, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.