Please use this identifier to cite or link to this item: https://doi.org/10.1007/s10456-014-9419-4
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dc.titleInflammatory lymphangiogenesis: Cellular mediators and functional implications
dc.contributor.authorTan, K.W.
dc.contributor.authorChong, S.Z.
dc.contributor.authorAngeli, V.
dc.date.accessioned2016-09-06T08:19:11Z
dc.date.available2016-09-06T08:19:11Z
dc.date.issued2014-04-01
dc.identifier.citationTan, K.W., Chong, S.Z., Angeli, V. (2014-04-01). Inflammatory lymphangiogenesis: Cellular mediators and functional implications. Angiogenesis 17 (2) : 373-381. ScholarBank@NUS Repository. https://doi.org/10.1007/s10456-014-9419-4
dc.identifier.issn15737209
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/126732
dc.description.abstractIn adult mammals, lymphatic vessels have been shown to respond to their environment by undergoing lymphangiogenesis, the formation of new lymphatic vessels from preexisting ones. Accumulating experimental and preclinical studies demonstrate that lymphangiogenesis is associated with many inflammatory diseases and may represent an attractive therapeutic target for inflammatory diseases. Thus, a better understanding of how lymphangiogenesis is regulated and contribution to inflammation is critical and may benefit clinical research targeting chronic inflammatory diseases. This review discusses the biological functions of lymphangiogenesis during inflammation and our current understanding of the key cellular players that can either support or limit lymphangiogenesis. Current data suggest that the context and time frame in which lymphangiogenesis occurs will determine its impact on the course of inflammation. © 2014 Springer Science+Business Media Dordrecht.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1007/s10456-014-9419-4
dc.sourceScopus
dc.subjectCell trafficking
dc.subjectFibroblastic reticular cells
dc.subjectInflammation
dc.subjectLymph node
dc.subjectLymphangiogenesis
dc.subjectLymphocytes
dc.subjectMacrophages
dc.subjectNeutrophils
dc.typeArticle
dc.contributor.departmentMICROBIOLOGY
dc.description.doi10.1007/s10456-014-9419-4
dc.description.sourcetitleAngiogenesis
dc.description.volume17
dc.description.issue2
dc.description.page373-381
dc.description.codenAGIOF
dc.identifier.isiut000334407600006
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