Please use this identifier to cite or link to this item:
|Title:||Concise synthesis of the cell cycle inhibitor demothoxyfumitremorgin C||Authors:||Wang, H.
|Issue Date:||16-Jun-1997||Citation:||Wang, H., Ganesan, A. (1997-06-16). Concise synthesis of the cell cycle inhibitor demothoxyfumitremorgin C. Tetrahedron Letters 38 (24) : 4327-4328. ScholarBank@NUS Repository. https://doi.org/10.1016/S0040-4039(97)00892-7||Abstract:||Reaction of the imine derived from L-tryptophan methyl ester and senecialdehyde with Fmoc-L-Pro-Cl induces an acyliminium Pictet-Spengler condensation, yielding a mixture of cis and trans tetrahydro-β-carbolines. Deprotection of the cis product with concomitant diketopiperazine formation afforded the natural product in 20% overall yield.||Source Title:||Tetrahedron Letters||URI:||http://scholarbank.nus.edu.sg/handle/10635/111834||ISSN:||00404039||DOI:||10.1016/S0040-4039(97)00892-7|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jun 30, 2020
WEB OF SCIENCETM
checked on Jun 23, 2020
checked on Jun 27, 2020
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.