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|Title:||Assembly of the TAN-1057 A/B heterocycle from a dehydroalanine precursor||Authors:||Lin, P.
|Issue Date:||2000||Citation:||Lin, P.,Ganesan, A. (2000). Assembly of the TAN-1057 A/B heterocycle from a dehydroalanine precursor. Synthesis (14) : 2127-2130. ScholarBank@NUS Repository.||Abstract:||A tandem reaction process was used to form the tetrahydropyrimidinone core of the TAN-1057 A and B dipeptide antibiotics. Michael addition of ammonia to a dehydroalanine derivative, followed by intramolecular displacement of an S-methylisothiourea assembles the tetrahydropyrimidinone in one-step.||Source Title:||Synthesis||URI:||http://scholarbank.nus.edu.sg/handle/10635/111790||ISSN:||00397881|
|Appears in Collections:||Staff Publications|
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