Please use this identifier to cite or link to this item: https://doi.org/10.1038/eye.2011.218
Title: Validity of EuroQOL-5D, time trade-off, and standard gamble for age-related macular degeneration in the Singapore population
Authors: Au Eong, K.G.
Chan, E.W.
Luo, N. 
Wong, S.H.
Tan, N.W.H.
Lim, T.H.
Wagle, A.M.
Keywords: age-related macular degeneration
quality of life
utility values
Issue Date: Mar-2012
Citation: Au Eong, K.G., Chan, E.W., Luo, N., Wong, S.H., Tan, N.W.H., Lim, T.H., Wagle, A.M. (2012-03). Validity of EuroQOL-5D, time trade-off, and standard gamble for age-related macular degeneration in the Singapore population. Eye 26 (3) : 379-388. ScholarBank@NUS Repository. https://doi.org/10.1038/eye.2011.218
Abstract: Background/aims: Utility values of age-related macular degeneration (AMD) in Asian patients are unknown. This study aims to assess utility values and construct validity of the EuroQOL-5D (EQ-5D), time trade-off (TTO), and standard gamble (SG) instruments in the Singapore multi-ethnic AMD population. Methods: Cross-sectional, two-centre, institution-based study. Visual acuity (VA), clinical AMD severity, and utility scores on the EQ-5D, TTO, and SG were obtained from 338 AMD patients. VA was analysed in terms of the better-seeing eye (BEVA), worse-seeing eye (WEVA), and weighted average of both eyes (WVA). We evaluated SG on the perfect health-death (SG(death)) and binocular perfect vision-binocular blindness (SG(blindness)) scales. Construct validity was determined by testing a priorihypotheses relating the EQ-5D, TTO, and SG utility scores to VA and clinical AMD severity. Results: The mean utilities on the EQ-5D, TTO, SG(death), and SG(blindness) were 0.89, 0.81, 0.86, and 0.90, respectively. EQ-5D scores correlated weakly with BEVA, WEVA, and WVA (Pearson's correlation coefficients -0.291, -0.247, and -0.305 respectively, P
Source Title: Eye
URI: http://scholarbank.nus.edu.sg/handle/10635/108827
ISSN: 0950222X
DOI: 10.1038/eye.2011.218
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

28
checked on Jul 29, 2021

WEB OF SCIENCETM
Citations

29
checked on Jul 29, 2021

Page view(s)

84
checked on Aug 1, 2021

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.