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https://doi.org/10.1038/sj.bjc.6606085
| Title: | Mammographic density and its interaction with other breast cancer risk factors in an Asian population | Authors: | Wong, C.S. Lim, G.H. Gao, F. Jakes, R.W. Offman, J. Chia, K.S. Duffy, S.W. |
Keywords: | Asian population body mass index breast cancer breast density mammography |
Issue Date: | 1-Mar-2011 | Citation: | Wong, C.S., Lim, G.H., Gao, F., Jakes, R.W., Offman, J., Chia, K.S., Duffy, S.W. (2011-03-01). Mammographic density and its interaction with other breast cancer risk factors in an Asian population. British Journal of Cancer 104 (5) : 871-874. ScholarBank@NUS Repository. https://doi.org/10.1038/sj.bjc.6606085 | Abstract: | Background: Joint effects of mammographic density and other risk factors on breast cancer risk remain unclear. Methods: From The Singapore Breast Screening Project, we selected 491 cases and 982 controls. Mammographic density was measured quantitatively. Data analysis was by conditional logistic regression. Results: Density was a significant risk factor, adjusting for other factors. Density of 76-100% had an odds ratio of 5.54 (95% CI 2.38-12.90) compared with 0-10%. Density had significant interactions with body mass index and oral contraceptive use (P=0.02).Conclusions:Percent density increases breast cancer risk in addition to effects of other risk factors, and modifies the effects of BMI and OCs. © 2011 Cancer Research UK All rights reserved. | Source Title: | British Journal of Cancer | URI: | http://scholarbank.nus.edu.sg/handle/10635/108458 | ISSN: | 00070920 | DOI: | 10.1038/sj.bjc.6606085 |
| Appears in Collections: | Staff Publications |
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