Full Name
Loke,Paxton
Variants
Loke, P.
 
Main Affiliation
 
 

Publications

Results 1-20 of 24 (Search time: 0.004 seconds).

Issue DateTitleAuthor(s)
12001A comparison of three site-directed mutagenesis kitsLoke, P. ; Tiow Suan Sim 
21998Analysis of a conserved arginine R281L in catalysis in Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
31998Analysis of glutamines in catalysis in Cephalosporium acremonium isopenicillin N synthase by site-directed mutagenesisLoke, P. ; Tiow Suan Sim 
41998Catalytic activity in cephalosporium acremonium isopenicillin N synthase does not involve glutamine-234Loke, P. ; Tiow Suan Sim 
52001Cloning and sequence characterisation of falcipain-2 from Plasmodium falciparum Gombak A strain (Malaysia)Sim, T.-S. ; Loke, P. ; Singh, M. ; Lee, M.; Flotow, H.
62001Cloning, heterologous expression and purification of an isocitrate lyase from Streptomyces clavuligerus NRRL 3585Soh, B.S.; Loke, P. ; Sim, T.-S. 
71-Dec-1997Functional analysis of a conserved aspartate D218 in Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, J.; Sim, T.-S. 
81999Glutamine-230 influences enzyme solubility but not catalysis in Streptomyces clavuligerus isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
92002Molecular cloning and functional characterisation of VanX, a D-alanyl-D-alanine dipeptidase from Streptomyces coelicolor A3(2)Tan, A.L.; Loke, P. ; Sim, T.-S. 
102000Molecular cloning, heterologous expression, and functional characterisation of a malate synthase gene from Streptomyces coelicolor A3(2)Loke, P. ; Sim, T.-S. 
112000Molecular studies on isopenicillin N synthasesSim, T.S. ; Loke, P. 
122001Mutational analysis of conserved glycines 42 and 256 in Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
132000Mutational analysis of tyrosine-191 in the catalysis of Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
1415-Aug-1998Mutational evidence for the role of serine-283 in Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
152000PCR cloning, heterologous expression, and characterization of isopenicillin N synthase from Streptomyces lipmanii NRRL 3584Loke, P. ; Ng, C.P.; Sim, T.-S. 
162001PCR-mediated screening and cloning of a malate synthase gene from Streptomyces griseus NCIMB 9001Loke, P. ; Wee, J.; Keng Ing Seah; Sim, T.-S. 
172002Purification and characterization of recombinant malate synthase enzymes from streptomyces coelicolor a3(2) and s. clavuligerus Nrrl3585Loke, P. ; Goh, L.-L.; SOH BOON SENG ; Yeow, P.; Sim, T.-S. 
182001Replacement of arginine-171 and aspartate-453 in Streptomyces coelicolor malate synthase A by site-directed mutagenesis inactivates the enzymeGoh, L.-L.; Loke, P. ; Tiow Suan Sim 
192001Replacement of tyrosine-197 and the corresponding tyrosine-195 to isoleucine in Cephalosporium acremonium and Streptomyces clavuligerus isopenicillin N synthaseLoke, P. ; Tiow Suan Sim 
2015-Oct-1999Site-directed mutagenesis of arginine-89 supports the role of its guanidino side-chain in substrate binding by Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-S.