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Alan Prem Kumar

rp02898

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Full Name
Alan Prem Kumar
Variants
Kumar, A.P.
Kumar, A.
Prem Kumar, A.
Kumar, Alan Prem Rem
 
Main Affiliation
 
Faculty
 
Email
apkumar@nus.edu.sg
 
Other emails
 

Publications

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Department:  DEAN'S OFFICE (MEDICINE)
Author:  Shanmugam, M.K.

Results 1-20 of 21 (Search time: 0.004 seconds).

Issue DateTitleAuthor(s)
12013An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteinsSubramaniam, A.; Loo, S.Y.; Rajendran, P.; Manu, K.A. ; Perumal, E.; Li, F.; Shanmugam, M.K. ; Siveen, K.S.; Park, J.-I.; Ahn, K.S.; Hui, K.M.; Kumar, A.P. ; Sethi, G.
215-Nov-2010Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cellsChua, A.W.L.; Hay, H.S. ; Rajendran, P.; Shanmugam, M.K. ; Li, F.; Bist, P.; Koay, E.S.C.; Lim, L.H.K.; Kumar, A.P. ; Sethi, G.
3Nov-2011Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cellsKannaiyan, R.; Hay, H.S. ; Rajendran, P.; Li, F.; Shanmugam, M.K. ; Vali, S.; Abbasi, T.; Kapoor, S.; Sharma, A.; Kumar, A.P. ; Chng, W.-J.; Sethi, G.
4Apr-2012Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade In Vitro and In VivoRajendran, P.; Li, F.; Shanmugam, M.K. ; Kannaiyan, R.; Goh, J.; Wong, K. ; Wang, W.; Khin, E.; Tergaonkar, V.; Kumar, A. ; Luk, J.M.; Sethi, G.
5Oct-2013Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3Subramaniam, A.; Shanmugam, M.K. ; Ong, T.H.; Li, F.; Perumal, E.; Chen, L.; Vali, S.; Abbasi, T.; Kapoor, S.; Ahn, K.S.; Kumar, A.P. ; Hui, K.M.; Sethi, G.
615-Apr-2012First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathwayManu, K.A. ; Shanmugam, M.K. ; Ramachandran, L.; Li, F.; Fong, C.W.; Kumar, A.P. ; Tan, P. ; Sethi, G.
7Aug-2013Garcinol, a polyisoprenylated benzophenone modulates multiple proinfl ammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinomaLi, F.; Shanmugam, M.K. ; Chen, L.; Chatterjee, S.; Basha, J.; Kumar, A.P. ; Kundu, T.K.; Sethi, G.
8May-2012Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1Rajendran, P.; Li, F.; Shanmugam, M.K. ; Vali, S.; Abbasi, T.; Kapoor, S.; Ahn, K.S.; Kumar, A.P. ; Sethi, G.
91-Oct-2011Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate modelShanmugam, M.K. ; Manu, K.A. ; Ong, T.H.; Ramachandran, L.; Surana, R.; Bist, P.; Lim, L.H.K.; Prem Kumar, A. ; Hui, K.M.; Sethi, G.
102-Nov-2012Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancerRamachandran, L.; Manu, K.A. ; Shanmugam, M.K. ; Li, F.; Siveen, K.S.; Vali, S.; Kapoor, S.; Abbasi, T.; Surana, R.; Smoot, D.T.; Ashktorab, H.; Tan, P. ; Ahn, K.S.; Yap, C.W. ; Kumar, A.P. ; Sethi, G.
1115-Nov-2012Key cell signaling pathways modulated by zerumbone: Role in the prevention and treatment of cancerPrasannan, R.; Kalesh, K.A.; Shanmugam, M.K. ; Nachiyappan, A.; Ramachandran, L.; Nguyen, A.H.; Kumar, A.P. ; Lakshmanan, M.; Ahn, K.S.; Sethi, G.
12Jan-2013Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinomaSubramaniam, A.; Shanmugam, M.K. ; Perumal, E.; Li, F.; Nachiyappan, A.; Dai, X.; Swamy, S.N.; Ahn, K.S.; Kumar, A.P. ; Tan, B.K.H.; Hui, K.M.; Sethi, G.
132013Role of NF-κB in tumorigenesisShanmugam, M.K. ; Kumar, A.P. ; Tan, B.K.H.; Sethi, G.
142014Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene productsManu, K.A.; Shanmugam, M.K. ; Li, F.; Chen, L.; Siveen, K.S.; Ahn, K.S.; Kumar, A.P. ; Sethi, G.
1515-Mar-2011Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivoRajendran, P.; Ong, T.H.; Chen, L.; Li, F.; Shanmugam, M.K. ; Vali, S.; Abbasi, T.; Kapoor, S.; Sharma, A.; Kumar, A.P. ; Hui, K.M.; Sethi, G.
161-Dec-2013Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancerShrimali, D.; Shanmugam, M.K. ; Kumar, A.P. ; Zhang, J.; Tan, B.K.H.; Ahn, K.S.; Sethi, G.
1728-Jul-2012Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancerShanmugam, M.K. ; Nguyen, A.H.; Kumar, A.P. ; Tan, B.K.H.; Sethi, G.
181-Jun-2013Ursolic acid in cancer prevention and treatment: Molecular targets, pharmacokinetics and clinical studiesShanmugam, M.K. ; Dai, X.; Kumar, A.P. ; Tan, B.K.H.; Sethi, G.; Bishayee, A.
19Jul-2011Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude miceShanmugam, M.K. ; Rajendran, P.; Li, F.; Nema, T.; Vali, S.; Abbasi, T.; Kapoor, S.; Sharma, A.; Kumar, A.P. ; Ho, P.C. ; Hui, K.M.; Sethi, G.
202014γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse modelSiveen, K.S.; Ahn, K.S.; Ong, T.H.; Shanmugam, M.K. ; Li, F.; Yap, W.N.; Kumar, A.P. ; Fong, C.W.; Tergaonkar, V.; Hui, K.M. ; Sethi, G.