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https://scholarbank.nus.edu.sg/handle/10635/93558
| Title: | Determination of pyrrolizidine alkaloids in comfrey by liquid chromatography-electrospray ionization mass spectrometry | Authors: | Liu, F. Wan, S.Y. Jiang, Z. Li, S.F.Y. Ong, E.S. Osorio, J.C.C. |
Keywords: | Liquid chromatography-electrospray ionization mass spectrometry Lycopsamine Orbitrap MS Pressurized hot water extraction Symphytum officinale L. |
Issue Date: | 15-Dec-2009 | Citation: | Liu, F., Wan, S.Y., Jiang, Z., Li, S.F.Y., Ong, E.S., Osorio, J.C.C. (2009-12-15). Determination of pyrrolizidine alkaloids in comfrey by liquid chromatography-electrospray ionization mass spectrometry. Talanta 80 (2) : 916-923. ScholarBank@NUS Repository. | Abstract: | Symphytum officinale L. (comfrey) is a medicinal plant commonly used in decoctions and aliments. Besides therapeutic bioactive compounds present in the herb, it is found to contain hepatotoxic pyrrolizidine alkaloids (PAs), such as lycopsamine and others. In the present study, PAs such as lycopsamine, echimidine and lasiocarpine were determined using electrospray liquid chromatography-mass spectrometry (LC-MS) with the method precision (relative standard deviation, RSD) | Source Title: | Talanta | URI: | http://scholarbank.nus.edu.sg/handle/10635/93558 | ISSN: | 00399140 |
| Appears in Collections: | Staff Publications |
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