Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/93558
Title: Determination of pyrrolizidine alkaloids in comfrey by liquid chromatography-electrospray ionization mass spectrometry
Authors: Liu, F.
Wan, S.Y.
Jiang, Z.
Li, S.F.Y. 
Ong, E.S.
Osorio, J.C.C.
Keywords: Liquid chromatography-electrospray ionization mass spectrometry
Lycopsamine
Orbitrap MS
Pressurized hot water extraction
Symphytum officinale L.
Issue Date: 15-Dec-2009
Citation: Liu, F., Wan, S.Y., Jiang, Z., Li, S.F.Y., Ong, E.S., Osorio, J.C.C. (2009-12-15). Determination of pyrrolizidine alkaloids in comfrey by liquid chromatography-electrospray ionization mass spectrometry. Talanta 80 (2) : 916-923. ScholarBank@NUS Repository.
Abstract: Symphytum officinale L. (comfrey) is a medicinal plant commonly used in decoctions and aliments. Besides therapeutic bioactive compounds present in the herb, it is found to contain hepatotoxic pyrrolizidine alkaloids (PAs), such as lycopsamine and others. In the present study, PAs such as lycopsamine, echimidine and lasiocarpine were determined using electrospray liquid chromatography-mass spectrometry (LC-MS) with the method precision (relative standard deviation, RSD)
Source Title: Talanta
URI: http://scholarbank.nus.edu.sg/handle/10635/93558
ISSN: 00399140
Appears in Collections:Staff Publications

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