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|Title:||Determination of pyrrolizidine alkaloids in comfrey by liquid chromatography-electrospray ionization mass spectrometry|
|Keywords:||Liquid chromatography-electrospray ionization mass spectrometry|
Pressurized hot water extraction
Symphytum officinale L.
|Citation:||Liu, F., Wan, S.Y., Jiang, Z., Li, S.F.Y., Ong, E.S., Osorio, J.C.C. (2009-12-15). Determination of pyrrolizidine alkaloids in comfrey by liquid chromatography-electrospray ionization mass spectrometry. Talanta 80 (2) : 916-923. ScholarBank@NUS Repository.|
|Abstract:||Symphytum officinale L. (comfrey) is a medicinal plant commonly used in decoctions and aliments. Besides therapeutic bioactive compounds present in the herb, it is found to contain hepatotoxic pyrrolizidine alkaloids (PAs), such as lycopsamine and others. In the present study, PAs such as lycopsamine, echimidine and lasiocarpine were determined using electrospray liquid chromatography-mass spectrometry (LC-MS) with the method precision (relative standard deviation, RSD)|
|Appears in Collections:||Staff Publications|
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