Please use this identifier to cite or link to this item:
https://doi.org/10.1039/c1an15143f
Title: | Using liquid crystals as a readout system in urinary albumin assays | Authors: | Alino, V.J. Yang, K.-L. |
Issue Date: | 21-Aug-2011 | Citation: | Alino, V.J., Yang, K.-L. (2011-08-21). Using liquid crystals as a readout system in urinary albumin assays. Analyst 136 (16) : 3307-3313. ScholarBank@NUS Repository. https://doi.org/10.1039/c1an15143f | Abstract: | Detecting human serum albumin (HSA) in urine samples is a standard procedure for the diagnosis of kidney problems and the prognosis of patients with chronic kidney diseases (CKDs). In this study, we developed a HSA assay by incorporating a thin layer of liquid crystals (LCs) as a readout system such that the presence of HSA in urine samples can be detected as optical signals. In combination with dilution protocols, this assay can be used to estimate the concentration range of HSA simply by counting the number of bright spots. Our results show that the assay can detect HSA at concentrations as low as 15 μg mL -1. It is anticipated that this assay can provide a faster and simpler alternative for the diagnosis and prognosis of patients with kidney diseases. © 2011 The Royal Society of Chemistry. | Source Title: | Analyst | URI: | http://scholarbank.nus.edu.sg/handle/10635/90466 | ISSN: | 00032654 | DOI: | 10.1039/c1an15143f |
Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.