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https://doi.org/10.1002/anie.201007841
| Title: | Ultrasensitive near-infrared Raman reporters for SERS-based in vivo cancer detection | Authors: | Samanta, A. Maiti, K.K. Soh, K.-S. Liao, X. Vendrell, M. Dinish, U.S. Yun, S.-W. Bhuvaneswari, R. Kim, H. Rautela, S. Chung, J. Olivo, M. Chang, Y.-T. |
Keywords: | chemisorption combinatorial chemistry high-throughput screening nanoparticles Raman spectroscopy |
Issue Date: | 27-Jun-2011 | Citation: | Samanta, A., Maiti, K.K., Soh, K.-S., Liao, X., Vendrell, M., Dinish, U.S., Yun, S.-W., Bhuvaneswari, R., Kim, H., Rautela, S., Chung, J., Olivo, M., Chang, Y.-T. (2011-06-27). Ultrasensitive near-infrared Raman reporters for SERS-based in vivo cancer detection. Angewandte Chemie - International Edition 50 (27) : 6089-6092. ScholarBank@NUS Repository. https://doi.org/10.1002/anie.201007841 | Abstract: | Of good report: Synthesis and screening of an 80-member tricarbocyanine library identified CyNAMLA-381 as a near-IR surface-enhanced Raman spectroscopy (SERS) reporter with good signal stability and higher sensitivity than the standard. Encapsulation of CyNAMLA-381 on gold nanoparticles and conjugation to an antibody afforded SERS nanotags with excellent sensitivity, stability, and tumor specificity in xenograft models (see picture). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. | Source Title: | Angewandte Chemie - International Edition | URI: | http://scholarbank.nus.edu.sg/handle/10635/77335 | ISSN: | 14337851 | DOI: | 10.1002/anie.201007841 |
| Appears in Collections: | Staff Publications |
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