Please use this identifier to cite or link to this item: https://doi.org/10.1002/anie.201007841
Title: Ultrasensitive near-infrared Raman reporters for SERS-based in vivo cancer detection
Authors: Samanta, A.
Maiti, K.K.
Soh, K.-S.
Liao, X.
Vendrell, M.
Dinish, U.S.
Yun, S.-W.
Bhuvaneswari, R.
Kim, H.
Rautela, S.
Chung, J.
Olivo, M.
Chang, Y.-T. 
Keywords: chemisorption
combinatorial chemistry
high-throughput screening
nanoparticles
Raman spectroscopy
Issue Date: 27-Jun-2011
Citation: Samanta, A., Maiti, K.K., Soh, K.-S., Liao, X., Vendrell, M., Dinish, U.S., Yun, S.-W., Bhuvaneswari, R., Kim, H., Rautela, S., Chung, J., Olivo, M., Chang, Y.-T. (2011-06-27). Ultrasensitive near-infrared Raman reporters for SERS-based in vivo cancer detection. Angewandte Chemie - International Edition 50 (27) : 6089-6092. ScholarBank@NUS Repository. https://doi.org/10.1002/anie.201007841
Abstract: Of good report: Synthesis and screening of an 80-member tricarbocyanine library identified CyNAMLA-381 as a near-IR surface-enhanced Raman spectroscopy (SERS) reporter with good signal stability and higher sensitivity than the standard. Encapsulation of CyNAMLA-381 on gold nanoparticles and conjugation to an antibody afforded SERS nanotags with excellent sensitivity, stability, and tumor specificity in xenograft models (see picture). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title: Angewandte Chemie - International Edition
URI: http://scholarbank.nus.edu.sg/handle/10635/77335
ISSN: 14337851
DOI: 10.1002/anie.201007841
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