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Please use this identifier to cite or link to this item: https://doi.org/10.1039/c1ob05519d
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dc.titleSynthesis and characterization of a cell-permeable near-infrared fluorescent deoxyglucose analogue for cancer cell imaging
dc.contributor.authorVendrell, M.
dc.contributor.authorSamanta, A.
dc.contributor.authorYun, S.-W.
dc.contributor.authorChang, Y.-T.
dc.date.accessioned2014-06-23T05:51:15Z
dc.date.available2014-06-23T05:51:15Z
dc.date.issued2011-07-07
dc.identifier.citationVendrell, M., Samanta, A., Yun, S.-W., Chang, Y.-T. (2011-07-07). Synthesis and characterization of a cell-permeable near-infrared fluorescent deoxyglucose analogue for cancer cell imaging. Organic and Biomolecular Chemistry 9 (13) : 4760-4762. ScholarBank@NUS Repository. https://doi.org/10.1039/c1ob05519d
dc.identifier.issn14770520
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/77129
dc.description.abstractWe report the synthesis and characterization of a novel NIR fluorescent deoxyglucose analogue, CyNE 2-DG. Experiments in different cell lines showed a preferential uptake of CyNE 2-DG in cancer cells and its effective competition with unlabeled d-glucose. Cell imaging experiments demonstrated the superior cell-permeability of CyNE 2-DG over the NIR standard IRDye 800CW 2-DG, and validated its application for cancer cell imaging in the NIR region. © The Royal Society of Chemistry 2011.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1039/c1ob05519d
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1039/c1ob05519d
dc.description.sourcetitleOrganic and Biomolecular Chemistry
dc.description.volume9
dc.description.issue13
dc.description.page4760-4762
dc.identifier.isiut000291654800009
Appears in Collections:Staff Publications

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