Multicomponent approach in the synthesis of 2,2,6-trisubstituted morpholine derivatives

Please use this identifier to cite or link to this item: https://doi.org/10.1021/ol3024105

Title:	Multicomponent approach in the synthesis of 2,2,6-trisubstituted morpholine derivatives
Authors:	Zhou, J. Zhou, L. Yeung, Y.-Y.
Issue Date:	19-Oct-2012
Citation:	Zhou, J., Zhou, L., Yeung, Y.-Y. (2012-10-19). Multicomponent approach in the synthesis of 2,2,6-trisubstituted morpholine derivatives. Organic Letters 14 (20) : 5250-5253. ScholarBank@NUS Repository. https://doi.org/10.1021/ol3024105
Abstract:	An efficient synthesis of 2,2,6-trisubstituted morpholine is described which involves a multicomponent process by simply mixing epichlorohydrin, N-bromosuccinimide, nosyl amide, and an olefin. The products contain chloride handles which are suitable for further modification. © 2012 American Chemical Society.
Source Title:	Organic Letters
URI:	http://scholarbank.nus.edu.sg/handle/10635/76602
ISSN:	15237060
DOI:	10.1021/ol3024105
Appears in Collections:	Staff Publications

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