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Title: Design and synthesis of fluorogenic substrates that target protein phosphatases
Authors: Zhu, Q. 
Huang, X.
Chen, G.Y.J. 
Yao, S.Q. 
Keywords: Enzyme
High throughput
Issue Date: 19-Jan-2004
Citation: Zhu, Q., Huang, X., Chen, G.Y.J., Yao, S.Q. (2004-01-19). Design and synthesis of fluorogenic substrates that target protein phosphatases. Tetrahedron Letters 45 (4) : 707-710. ScholarBank@NUS Repository.
Abstract: We have successfully designed and synthesized new fluorogenic probes that specifically target different classes of protein phosphatases. The fluorescence profiles of the probes have been studied using 12 different phosphatases, and results showed that, besides alkaline and tyrosine phosphatases, our probes were able to detect serine/threonine as well as acid phosphatases. © 2003 Elsevier Ltd. All rights reserved.
Source Title: Tetrahedron Letters
ISSN: 00404039
DOI: 10.1016/j.tetlet.2003.11.058
Appears in Collections:Staff Publications

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