Bicyclic guanidine-catalyzed direct asymmetric allylic addition of N-aryl alkylidene-succinimides

Please use this identifier to cite or link to this item: https://doi.org/10.1002/chem.201002183

Title:	Bicyclic guanidine-catalyzed direct asymmetric allylic addition of N-aryl alkylidene-succinimides
Authors:	Wang, J. Liu, H. Fan, Y. Yang, Y. Jiang, Z. Tan, C.-H.
Keywords:	allylation asymmetric synthesis guanidine Mannich reactions
Issue Date:	8-Nov-2010
Citation:	Wang, J., Liu, H., Fan, Y., Yang, Y., Jiang, Z., Tan, C.-H. (2010-11-08). Bicyclic guanidine-catalyzed direct asymmetric allylic addition of N-aryl alkylidene-succinimides. Chemistry - A European Journal 16 (42) : 12534-12537. ScholarBank@NUS Repository. https://doi.org/10.1002/chem.201002183
Abstract:	Enantio-enriched maleimides and succinimides that can be used to prepare aza-heterocycles with multiple chiral centers are obtained from the bicyclic guanidine-catalyzed direct asymmetric allylic addition of N-aryl alkylidene-succinimides to imines. NMR studies and deuterium-exchange experiments were used to study the intermediates in the reaction. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title:	Chemistry - A European Journal
URI:	http://scholarbank.nus.edu.sg/handle/10635/75653
ISSN:	09476539
DOI:	10.1002/chem.201002183
Appears in Collections:	Staff Publications

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