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https://scholarbank.nus.edu.sg/handle/10635/75540
| Title: | Aldol reaction under solvent-free conditions: Highly stereoselective synthesis of 1,3-amino alcohols | Authors: | Loh, T.-P. Huang, J.-M. Goh, S.-H. Vittal, J.J. |
Issue Date: | 4-May-2000 | Citation: | Loh, T.-P.,Huang, J.-M.,Goh, S.-H.,Vittal, J.J. (2000-05-04). Aldol reaction under solvent-free conditions: Highly stereoselective synthesis of 1,3-amino alcohols. Organic Letters 2 (9) : 1291-1294. ScholarBank@NUS Repository. | Abstract: | (formula presented) A method for the highly stereoselective synthesis of 1,3-amino alcohols based on the indium trichloride-catalyzed Mukaiyama aldol reaction of keto ester (R,S)-1 under solvent-free conditions has been developed. The high selectivity observed can be explained on the basis of the shielding of one face by a remote substituent. | Source Title: | Organic Letters | URI: | http://scholarbank.nus.edu.sg/handle/10635/75540 | ISSN: | 15237060 |
| Appears in Collections: | Staff Publications |
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