Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/75540
Title: Aldol reaction under solvent-free conditions: Highly stereoselective synthesis of 1,3-amino alcohols
Authors: Loh, T.-P. 
Huang, J.-M.
Goh, S.-H. 
Vittal, J.J. 
Issue Date: 4-May-2000
Source: Loh, T.-P.,Huang, J.-M.,Goh, S.-H.,Vittal, J.J. (2000-05-04). Aldol reaction under solvent-free conditions: Highly stereoselective synthesis of 1,3-amino alcohols. Organic Letters 2 (9) : 1291-1294. ScholarBank@NUS Repository.
Abstract: (formula presented) A method for the highly stereoselective synthesis of 1,3-amino alcohols based on the indium trichloride-catalyzed Mukaiyama aldol reaction of keto ester (R,S)-1 under solvent-free conditions has been developed. The high selectivity observed can be explained on the basis of the shielding of one face by a remote substituent.
Source Title: Organic Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/75540
ISSN: 15237060
Appears in Collections:Staff Publications

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