Please use this identifier to cite or link to this item: https://doi.org/10.1115/1.2170118
DC FieldValue
dc.titleMass transport and shear stress in a microchannel bioreactor: Numerical simulation and dynamic similarity
dc.contributor.authorZeng, Y.
dc.contributor.authorLee, T.-S.
dc.contributor.authorYu, P.
dc.contributor.authorRoy, P.
dc.contributor.authorLow, H.-T.
dc.date.accessioned2014-06-17T06:26:04Z
dc.date.available2014-06-17T06:26:04Z
dc.date.issued2006-04
dc.identifier.citationZeng, Y., Lee, T.-S., Yu, P., Roy, P., Low, H.-T. (2006-04). Mass transport and shear stress in a microchannel bioreactor: Numerical simulation and dynamic similarity. Journal of Biomechanical Engineering 128 (2) : 185-193. ScholarBank@NUS Repository. https://doi.org/10.1115/1.2170118
dc.identifier.issn01480731
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/60680
dc.description.abstractMicrochannel bioreactors have been used in many studies to manipulate and investigate the fluid microenvironment around cells. In this study, substrate concentrations and shear stresses at the base were computed from a three-dimensional numerical flow-model incorporating mass transport. Combined dimensionless parameters were developed from a simplified analysis. The numerical results of substrate concentration were well correlated by the combined parameters. The generalized results may find applications in design analysis of microchannel bioreactors. The mass transport and shear stress were related in a generalized result. Based on the generalized results and the condition of dynamic similarity, various means to isolate their respective effects on cells were considered. Copyright © 2006 by ASME.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1115/1.2170118
dc.sourceScopus
dc.subjectCell culture
dc.subjectMicrochannel bioreactor
dc.subjectShear stress
dc.subjectSubstrate concentration
dc.typeArticle
dc.contributor.departmentMECHANICAL ENGINEERING
dc.contributor.departmentBIOENGINEERING
dc.contributor.departmentTEMASEK LABORATORIES
dc.description.doi10.1115/1.2170118
dc.description.sourcetitleJournal of Biomechanical Engineering
dc.description.volume128
dc.description.issue2
dc.description.page185-193
dc.description.codenJBEND
dc.identifier.isiut000236455800003
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

28
checked on Nov 26, 2021

WEB OF SCIENCETM
Citations

30
checked on Nov 26, 2021

Page view(s)

92
checked on Nov 18, 2021

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.