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https://scholarbank.nus.edu.sg/handle/10635/53322
| Title: | Structural biology of RNA silencing and its functional implications | Authors: | Patel, D.J. Ma, J.-B. Yuan, Y.-R. Ye, K. Pei, Y. Kuryavyi, V. Malinina, L. Meister, G. Tuschl, T. |
Issue Date: | 2006 | Citation: | Patel, D.J., Ma, J.-B., Yuan, Y.-R., Ye, K., Pei, Y., Kuryavyi, V., Malinina, L., Meister, G., Tuschl, T. (2006). Structural biology of RNA silencing and its functional implications. Cold Spring Harbor Symposia on Quantitative Biology 71 : 81-93. ScholarBank@NUS Repository. | Abstract: | We outline structure-function contributions from our laboratories on protein-RNA recognition events that monitor siRNA length, 5′-phosphate and 2-nucleotide 3′ overhangs, as well as the architecture of Argonaute, its externally bound siRNA complex, and Argonaute-based models involving guide-strand-mediated mRNA binding, cleavage, and release. © 2006 Cold Spring Harbor Laboratory Press. | Source Title: | Cold Spring Harbor Symposia on Quantitative Biology | URI: | http://scholarbank.nus.edu.sg/handle/10635/53322 | ISSN: | 00917451 |
| Appears in Collections: | Staff Publications |
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