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|Title:||Structural biology of RNA silencing and its functional implications||Authors:||Patel, D.J.
|Issue Date:||2006||Citation:||Patel, D.J., Ma, J.-B., Yuan, Y.-R., Ye, K., Pei, Y., Kuryavyi, V., Malinina, L., Meister, G., Tuschl, T. (2006). Structural biology of RNA silencing and its functional implications. Cold Spring Harbor Symposia on Quantitative Biology 71 : 81-93. ScholarBank@NUS Repository.||Abstract:||We outline structure-function contributions from our laboratories on protein-RNA recognition events that monitor siRNA length, 5′-phosphate and 2-nucleotide 3′ overhangs, as well as the architecture of Argonaute, its externally bound siRNA complex, and Argonaute-based models involving guide-strand-mediated mRNA binding, cleavage, and release. © 2006 Cold Spring Harbor Laboratory Press.||Source Title:||Cold Spring Harbor Symposia on Quantitative Biology||URI:||http://scholarbank.nus.edu.sg/handle/10635/53322||ISSN:||00917451|
|Appears in Collections:||Staff Publications|
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