1. ScholarBank@NUS
  2. 1. Staff
  3. Staff Publications
Please use this identifier to cite or link to this item: https://doi.org/10.1074/jbc.M112.388702
DC FieldValue
dc.titleIsorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer
dc.contributor.authorRamachandran, L.
dc.contributor.authorManu, K.A.
dc.contributor.authorShanmugam, M.K.
dc.contributor.authorLi, F.
dc.contributor.authorSiveen, K.S.
dc.contributor.authorVali, S.
dc.contributor.authorKapoor, S.
dc.contributor.authorAbbasi, T.
dc.contributor.authorSurana, R.
dc.contributor.authorSmoot, D.T.
dc.contributor.authorAshktorab, H.
dc.contributor.authorTan, P.
dc.contributor.authorAhn, K.S.
dc.contributor.authorYap, C.W.
dc.contributor.authorKumar, A.P.
dc.contributor.authorSethi, G.
dc.date.accessioned2014-05-19T02:52:57Z
dc.date.available2014-05-19T02:52:57Z
dc.date.issued2012-11-02
dc.identifier.citationRamachandran, L., Manu, K.A., Shanmugam, M.K., Li, F., Siveen, K.S., Vali, S., Kapoor, S., Abbasi, T., Surana, R., Smoot, D.T., Ashktorab, H., Tan, P., Ahn, K.S., Yap, C.W., Kumar, A.P., Sethi, G. (2012-11-02). Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer. Journal of Biological Chemistry 287 (45) : 38028-38040. ScholarBank@NUS Repository. https://doi.org/10.1074/jbc.M112.388702
dc.identifier.issn00219258
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/53005
dc.description.abstractBackground: PPAR-γ, a nuclear transcription factor, plays a critical role in the development of gastric cancer (GC). Hence, novel agents that can modulate PPAR-γ cascade have a great potential for the treatment of GC. Results: Isorhamnetin (IH) modulates PPAR-γ pathway in GC. Conclusion: IH induces apoptosis through the activation of the PPAR-γ pathway. Significance: The study proposes a novel agent for GC treatment. © 2012 by The American Society for Biochemistry and Molecular Biology, Inc.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1074/jbc.M112.388702
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCANCER SCIENCE INSTITUTE OF SINGAPORE
dc.contributor.departmentDUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE
dc.contributor.departmentPHARMACY
dc.contributor.departmentPHARMACOLOGY
dc.description.doi10.1074/jbc.M112.388702
dc.description.sourcetitleJournal of Biological Chemistry
dc.description.volume287
dc.description.issue45
dc.description.page38028-38040
dc.description.codenJBCHA
dc.identifier.isiut000310642200037
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.