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Title: Engineered large spider eggcase silk protein for strong artificial fibers
Authors: Lin, Z. 
Deng, Q.
Liu, X.-Y. 
Yang, D. 
Keywords: artificial silk fiber
disulfide bond
silk protein
spider silk
Issue Date: 25-Feb-2013
Citation: Lin, Z., Deng, Q., Liu, X.-Y., Yang, D. (2013-02-25). Engineered large spider eggcase silk protein for strong artificial fibers. Advanced Materials 25 (8) : 1216-1220. ScholarBank@NUS Repository.
Abstract: A simple strategy is developed to produce large silk proteins in commercially available E. coli. The strategy is demonstrated for the production of a modified eggcase silk protein with a molecular weight of ∼378 kDa. Using a non-toxic water coagulation bath developed here, the recombinant protein is spun into artificial fibers that reach higher tenacity than its native counterpart. The strategy is generally applicable to synthesizing other types of large silk proteins with tandem repetitive domains. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title: Advanced Materials
ISSN: 09359648
DOI: 10.1002/adma.201204357
Appears in Collections:Staff Publications

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