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Title: Modeling and simulation of deformation of hydrogels responding to electric stimulus
Authors: Li, H. 
Luo, R.
Lam, K.Y. 
Keywords: Deformation
Electric stimulus
Functional engineered tissue
Mathematical modeling
Responsive hydrogel
Issue Date: 2007
Citation: Li, H., Luo, R., Lam, K.Y. (2007). Modeling and simulation of deformation of hydrogels responding to electric stimulus. Journal of Biomechanics 40 (5) : 1091-1098. ScholarBank@NUS Repository.
Abstract: A model for simulation of pH-sensitive hydrogels is refined in this paper to extend its application to electric-sensitive hydrogels, termed the refined multi-effect-coupling electric-stimulus (rMECe) model. By reformulation of the fixed-charge density and consideration of finite deformation, the rMECe model is able to predict the responsive deformations of the hydrogels when they are immersed in a bath solution subject to externally applied electric field. The rMECe model consists of nonlinear partial differential governing equations with chemo-electro-mechanical coupling effects and the fixed-charge density with electric-field effect. By comparison between simulation and experiment extracted from literature, the model is verified to be accurate and stable. The rMECe model performs quantitatively for deformation analysis of the electric-sensitive hydrogels. The influences of several physical parameters, including the externally applied electric voltage, initial fixed-charge density, hydrogel strip thickness, ionic strength and valence of surrounding solution, are discussed in detail on the displacement and average curvature of the hydrogels. © 2006 Elsevier Ltd. All rights reserved.
Source Title: Journal of Biomechanics
ISSN: 00219290
DOI: 10.1016/j.jbiomech.2006.04.012
Appears in Collections:Staff Publications

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