Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.biomaterials.2003.08.042
| Title: | Electrospun P(LLA-CL) nanofiber: A biomimetic extracellular matrix for smooth muscle cell and endothelial cell proliferation | Authors: | Mo, X.M. Xu, C.Y. Kotaki, M. Ramakrishna, S. |
Keywords: | Electrospinning Endothelial cell Nanofiber Poly(L-lactide-co-ε-caprolactone) Scaffold Smooth muscle cell |
Issue Date: | May-2004 | Citation: | Mo, X.M., Xu, C.Y., Kotaki, M., Ramakrishna, S. (2004-05). Electrospun P(LLA-CL) nanofiber: A biomimetic extracellular matrix for smooth muscle cell and endothelial cell proliferation. Biomaterials 25 (10) : 1883-1890. ScholarBank@NUS Repository. https://doi.org/10.1016/j.biomaterials.2003.08.042 | Abstract: | Poly(L-lactide-co-ε-caprolactone) [P(LLA-CL)] with L-lactide to ε-caprolactone ratio of 75 to 25 has been electrospun into nanofibers. The relationship between electrospinning parameters and fiber diameter has been investigated. The fiber diameter decreased with decreasing polymer concentration and with increasing electrospinning voltage. The X-ray diffractometer and differential scanning colorimeter results suggested that the electrospun nanofibers developed highly oriented structure in CL-unit sequences during the electrospinning process. The biocompatibility of the nanofiber scaffold has been investigated by culturing cells on the nanofiber scaffold. Both smooth muscle cell and endothelial cell adhered and proliferated well on the P(LLA-CL) nanofiber scaffolds. © 2003 Elsevier Ltd. All rights reserved. | Source Title: | Biomaterials | URI: | http://scholarbank.nus.edu.sg/handle/10635/51399 | ISSN: | 01429612 | DOI: | 10.1016/j.biomaterials.2003.08.042 |
| Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.